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CAS No 3562-84-3 , (3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone

  • Name: (3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone
  • Synonyms: Uricovac; Urinorm; Hipurik;Benzbromaron; Exurate;(3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone; Minuric; Desuric; Narcaricin; Normurat;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 161 - 163 C
  • Boiling Point:
  • Density: 1.709 g/cm3
  • Water Solubility: Insoluble
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 222-630-7
  • Molecular Weight: 424.08338
  • InchiKey: WHQCHUCQKNIQEC-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)
    17(21)12(19)8-9/h3-8,21H,2H2,1H3
  • Risk Statements: S36
  • Molecular Formula: C17H12Br2O3
  • Molecular Structure:CAS No:3562-84-3 (3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone

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References of (3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone
Title: Benzbromarone
CAS Registry Number: 3562-84-3
CAS Name: (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)methanone
Synonyms: 3,5-dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl ketone; 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethylbenzofuran; 2-ethyl-3-benzofuranyl 4-hydroxy-3,5-dibromophenyl ketone; 2-ethyl-3-(3,5-dibromo-4-hydroxybenzoyl)benzofuran; 2-ethyl-3-(3,5-dibromo-4-hydroxybenzoyl)oxaindene; 2-ethyl-3-benzofuryl 3,5-dibromo-4-hydroxyphenyl ketone
Manufacturers' Codes: L-2214; MJ-10061
Trademarks: Azubromaron (Azupharma); Desuric (Sanofi Winthrop); Max-Uric (Labinca); Minuric (R & C); Narcaricin (Heumann); Normurat (Grñenthal); Uricovac (Sanofi Winthrop); Urinorm (Torii)
Molecular Formula: C17H12Br2O3
Molecular Weight: 424.08
Percent Composition: C 48.15%, H 2.85%, Br 37.68%, O 11.32%
Literature References: Prepn: BE 553621 (1957 to Labaz); Buu-Hoi et al., J. Chem. Soc. 1957, 625; Buu-Hoi, Beaudet, US 3012042 (1961 to Soc. Belge l'Azote Prod. Chim. Marly). Structure-activity study: Delbarre et al., Chim. Ther. 3, 470 (1968). Pharmacology of hypouricemic effect: D. S. Sinclair, I. H. Fox, J. Rheumatol. 2, 437 (1975). Pharmacokinetic and clinical studies: T. F. Yu, ibid. 3, 305 (1976). Pharmacokinetics and biotransformation in man: H. Ferber et al., Eur. J. Clin. Pharmacol. 19, 431 (1981). HPLC determn in serum: H. Vergin et al., J. Chromatogr. 183, 383 (1980).
Properties: Yellowish prisms, mp 151°.
Melting point: mp 151°
Therap-Cat: Uricosuric.
Keywords: Uricosuric.