Home > Name List By 2 > 2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-N-(2, 6-dimethylphenyl)acetamide

CAS No 3416-26-0 , 2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-N-(2,
6-dimethylphenyl)acetamide

  • Name: 2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-N-(2,
    6-dimethylphenyl)acetamide
  • Synonyms: 3416-26-0; Corflazine; Klinium; Lidoflazinum;2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-N-(2,
    6-dimethylphenyl)acetamide; Lidoflazina [Italian];Clinium; Angex; Ordiflazine; Lidoflazin;
  • CAS Registry Number:
  • Flash Point: 336.4°C
  • Boiling Point: 632.6°Cat760mmHg
  • Density: 1.161g/cm3
  • Refractive index: 1.581
  • Safety Statements: Hazard Codes XnRisk Statements 22Safety Statements 36RTECS TK7910000
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 336.4°C
  • EINECS: 222-312-8
  • Molecular Weight: 491.615206
  • InchiKey: ZBIAKUMOEKILTF-UHFFFAOYSA-N
  • InChI: InChI=1S/C30H35F2N3O/c1-22-5-3-6-23(2)30(22)33-29(36)21-35-19-17-34(18-
    20-35)16-4-7-28(24-8-12-26(31)13-9-24)25-10-14-27(32)15-11-25/h3,5-6,
    8-15,28H,4,7,16-21H2,1-2H3,(H,33,36)
  • Risk Statements: 22
  • Molecular Formula: C30H35F2N3O
  • Molecular Structure:CAS No:3416-26-0 2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-N-(2,<br />6-dimethylphenyl)acetamide

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3416-26-0 Lidoflazine

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3416-26-0 LIDOFLAZINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
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References of 2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-N-(2,
6-dimethylphenyl)acetamide
Title: Lidoflazine
CAS Registry Number: 3416-26-0
CAS Name: 4-[4,4-Bis(4-fluorophenyl)butyl]-N-(2,6-dimethylphenyl)-1-piperazineacetamide
Synonyms: 4-[4,4-bis(p-fluorophenyl)butyl]-1-piperazineaceto-2￠,6￠-xylidide; 1-[4,4-di(4-fluorophenyl)butyl]-4-[(2,6-dimethylanilinocarbonyl)methyl]piperazine
Manufacturers' Codes: McN-JR-7094; R-7904
Trademarks: Angex (Janssen); Clinium (McNeil); Klinium (Janssen); Ordiflazine; Corflazine (Daltan)
Molecular Formula: C30H35F2N3O
Molecular Weight: 491.62
Percent Composition: C 73.29%, H 7.18%, F 7.73%, N 8.55%, O 3.25%
Literature References: Calcium blocking agent. Prepn: NL 6507312; H. K. F. Hermans, W. K. Schaper, US 3267104 (1965, 1966, both to Janssen). Crystal structure: G. Germain et al., Acta Crystallogr. 33B, 1971 (1977). Tissue specificity of calcium-blocking properties: J. M. Van Neuten, D. Wellens, Arch. Int. Pharmacodyn. Ther. 242, 329 (1979). Cardioprotective effects: W. Daenen, W. Flameng, Angiology 32, 543 (1981). Effects in angina: F. L. Gobel et al., Circulation 65, 1 Pt. 2, 127 (1982); W. Shapiro et al., ibid. 143.
Properties: Crystals, mp 159-161°. Almost insol in water (<0.01%), very sol in chloroform (>50%), but much less sol in other common organic solvents: W. K. Schaper et al., J. Pharmacol. Exp. Ther. 152, 265 (1966).
Melting point: mp 159-161°
Therap-Cat: Vasodilator (coronary).
Keywords: Calcium Channel Blocker; Piperazine Derivatives; Vasodilator (Coronary).