Home > Name List By a > Amidephrine

CAS No 3354-67-4 , Amidephrine

  • Name: Amidephrine
  • Synonyms: Amidephrine;N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide;
  • CAS Registry Number:
  • Flash Point: 214.3°C
  • Boiling Point: 430.7°C at 760 mmHg
  • Density: 1.311g/cm3
  • Refractive index: 1.59
  • Flash Point: 214.3°C
  • Molecular Weight: 244.313
  • InChI: InChI=1/C10H16N2O3S/c1-11-7-10(13)8-4-3-5-9(6-8)12-16(2,14)15/h3-6,10-13H,7H2,1-2H3
  • Molecular Formula: C10H16N2O3S
  • Molecular Structure:CAS No:3354-67-4 Amidephrine

Select to

3354-67-4 Amidephrine

  • Amidephrine, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
Contact Supplier

Select to

1/1
References of Amidephrine
Title: Amidephrine
CAS Registry Number: 3354-67-4
CAS Name: N-[3-[1-Hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide
Synonyms: 3￠-[1-hydroxy-2-(methylamino)ethyl]methanesulfonanilide
Manufacturers' Codes: MJ-1996
Molecular Formula: C10H16N2O3S
Molecular Weight: 244.31
Percent Composition: C 49.16%, H 6.60%, N 11.47%, O 19.65%, S 13.12%
Literature References: a1 Adrenoceptor agonist. Prepn: Larsen, Uloth, FR M3027 (1965 to Mead Johnson), C.A. 62, 13091a (1965); Uloth et al., J. Med. Chem. 9, 88 (1966). Pharmacology of the racemate: Dungan et al., Int. J. Neuropharmacol. 4, 219 (1965); Stanton et al., ibid. 235; of the isomers: Larsen, Lish, Nature 203, 1283 (1964); Buchthal, Jenkinson, Eur. J. Pharmacol. 10, 293 (1970). Toxicology: J. H. Weikel, Jr., K. H. Harper, Toxicol. Appl. Pharmacol. 23, 589 (1972).
Properties: Crystals, mp 159-161°. pKa 9.1.
Melting point: mp 159-161°
pKa: pKa 9.1
 
Derivative Type: Methanesulfonate
CAS Registry Number: 1421-68-7
Synonyms: Amidephrine mesylate
Manufacturers' Codes: MJ-5190
Trademarks: Fentrinol (Frika)
Molecular Formula: C10H16N2O3S.CH3SO3H
Molecular Weight: 340.42
Percent Composition: C 38.81%, H 5.92%, N 8.23%, O 28.20%, S 18.84%
Properties: Crystals from ethanol, mp 207-209°. LD50 in mice (mg/kg): 2284 orally, 780 i.p., 190 i.v., 1990 s.c.; in male, female Mead Johnson rats (mg/kg): 229, 36 orally; 144, 25 i.p.; in male, female Sprague-Dawley rats (mg/kg): 24, 13 orally; in rabbits (mg/kg): 12 orally, 7.5 intradermally (Weikel, Harper).
Melting point: mp 207-209°
Toxicity data: LD50 in mice (mg/kg): 2284 orally, 780 i.p., 190 i.v., 1990 s.c.; in male, female Mead Johnson rats (mg/kg): 229, 36 orally; 144, 25 i.p.; in male, female Sprague-Dawley rats (mg/kg): 24, 13 orally; in rabbits (mg/kg): 12 orally, 7.5 intradermally (Weikel, Harper)
 
Therap-Cat: Vasoconstrictor; decongestant (nasal).
Keywords: a-Adrenergic Agonist; Decongestant.