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CAS No 325715-02-4 , N-methyl-N-[3-[3-(thiophene-2-carbonyl)pyrazolo[1,
5-a]pyrimidin-7-yl]phenyl]acetamide

  • Name: N-methyl-N-[3-[3-(thiophene-2-carbonyl)pyrazolo[1,
    5-a]pyrimidin-7-yl]phenyl]acetamide
  • Synonyms: AC1O52E3;N-methyl-N-[3-[3-(thiophene-2-carbonyl)pyrazolo[1,
    5-a]pyrimidin-7-yl]phenyl]acetamide; ZINC00538650; Indiplon (USAN/INN); CHEMBL262075; UNII-8BT63DA42E; NBI 34060;325715-02-4; NBI-34060; AC-2358;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.35g/cm3
  • Refractive index: 1.699
  • Flash Point: °C
  • Molecular Weight: 376.43164
  • InchiKey: CBIAWPMZSFFRGN-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H16N4O2S/c1-13(25)23(2)15-6-3-5-14(11-15)17-8-9-21-20-16(12-
    22-24(17)20)19(26)18-7-4-10-27-18/h3-12H,1-2H3
  • Molecular Formula: C20H16N4O2S
  • Molecular Structure:CAS No:325715-02-4 N-methyl-N-[3-[3-(thiophene-2-carbonyl)pyrazolo[1,<br />5-a]pyrimidin-7-yl]phenyl]acetamide

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References of N-methyl-N-[3-[3-(thiophene-2-carbonyl)pyrazolo[1,
5-a]pyrimidin-7-yl]phenyl]acetamide
Title: Indiplon
CAS Registry Number: 325715-02-4
CAS Name: N-Methyl-N-[3-[3-(2-thienylcarbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]acetamide
Manufacturers' Codes: CL-285489; NBI-34060
Molecular Formula: C20H16N4O2S
Molecular Weight: 376.43
Percent Composition: C 63.81%, H 4.28%, N 14.88%, O 8.50%, S 8.52%
Literature References: Short-acting nonbenzodiazepine sedative; high-affinity a1-selective allosteric potentiator of GABAA receptor function. Prepn: J. P. Dusza et al., US 4521422 (1985 to Am. Cyanamid). See also: idem et al., US 6399621 (2002 to Am. Cyanamid). Receptor binding studies: S. K. Sullivan et al., J. Pharmacol. Exp. Ther. 311, 537 (2004). In vivo pharmacology: A. C. Foster et al., ibid. 547. Review of clinical development: D. N. Neubauer, Expert Opin. Invest. Drugs 14, 1269-1276 (2005).
Properties: Yellow solid.
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.14.
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Imidazopyridines.