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CAS No 322-79-2 , 2-acetyloxy-4-(trifluoromethyl)benzoic acid Search by region : India

  • Name: 2-acetyloxy-4-(trifluoromethyl)benzoic acid
  • Synonyms: 2-Acetoxy-4-trifluoromethylbenzoic acid; 322-79-2;2-acetyloxy-4-(trifluoromethyl)benzoic acid; 2-(Acetyloxy)-4-(trifluoromethyl)benzoic acid; UR 1501;Disgren; Triflusalum [INN-Latin];
  • CAS Registry Number:
  • Flash Point: 144.9 °C
  • Boiling Point: 316 °C at 760 mmHg
  • Density: 1.433 g/cm3
  • Refractive index: 1.483
  • Flash Point: 144.9 °C
  • EINECS: 206-297-5
  • Molecular Weight: 248.15539
  • InchiKey: RMWVZGDJPAKBDE-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H7F3O4/c1-5(14)17-8-4-6(10(11,12)13)2-3-7(8)9(15)16/h2-4H,
    1H3,(H,15,16)
  • Molecular Formula: C10H7F3O4
  • Molecular Structure:CAS No:322-79-2 2-acetyloxy-4-(trifluoromethyl)benzoic acid

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References of 2-acetyloxy-4-(trifluoromethyl)benzoic acid
Title: Triflusal
CAS Registry Number: 322-79-2
CAS Name: 2-(Acetyloxy)-4-(trifluoromethyl)benzoic acid
Synonyms: a,a,a-trifluoro-2,4-cresotic acid acetate; acetyl-4-trifluoromethylsalicylic acid
Manufacturers' Codes: UR-1501
Trademarks: Disgren (Uriach)
Molecular Formula: C10H7F3O4
Molecular Weight: 248.16
Percent Composition: C 48.40%, H 2.84%, F 22.97%, O 25.79%
Literature References: Analog of aspirin, q.v.; inhibits platelet aggregation. Prepn of free acid: M. Hauptschein, US 3019253 (1962 to Pennsalt). Inhibition of platelet aggregation in man and rat: J. Garcia-Rafanell, J. Morell, Therapie 32, 337 (1977). Effect on blood coagulation: M. Rutllant et al., Curr. Ther. Res. 22, 510 (1977). Pharmacokinetics: V. Rimbau et al., Arch. Farmacol. Toxicol. 7, 11 (1981). Clinical studies: R. M. Masso et al., Curr. Ther. Res. 25, 791 (1979); E. Sala-Planell et al., Angiologia 33, 71 (1981).
Properties: White cryst solid from petr ether/ether, mp 120-122° (upon slow heating); 110-112° (upon quick heating). Misc with ethanol. Practically insol in water.
Melting point: mp 120-122° (upon slow heating); 110-112° (upon quick heating)
Therap-Cat: Antithrombotic.
Keywords: Antithrombotic.