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CAS No 30653-83-9 , Benzamide,5-amino-N-butyl-2-(2-propyn-1-yloxy)-

  • Name: Benzamide,5-amino-N-butyl-2-(2-propyn-1-yloxy)-
  • Synonyms: Benzamide,5-amino-N-butyl-2-(2-propynyloxy)- (8CI,9CI); Parsal; Parsalmide;Benzamide,5-amino-N-butyl-2-(2-propyn-1-yloxy)-; MY 41-6;
  • CAS Registry Number:
  • Flash Point: 210.3°C
  • Boiling Point: 424°Cat760mmHg
  • Density: 1.107g/cm3
  • Refractive index: 1.558
  • Safety Statements: Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 210.3°C
  • EINECS: 250-274-2
  • Molecular Weight: 0
  • InChI: InChI=1/C14H18N2O2/c1-3-5-8-16-14(17)12-10-11(15)6-7-13(12)18-9-4-2/h2,6-7,10H,3,5,8-9,15H2,1H3,(H,16,17)
  • Molecular Formula: C14H18N2O2
  • Molecular Structure:CAS No:30653-83-9 Benzamide,5-amino-N-butyl-2-(2-propyn-1-yloxy)-

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30653-83-9 Parsalmide

  • China Shanghai ChemVia Co., Ltd [Manufacturer]
  • Tel: +86-21-6875-8016 (Sunny Liu)/ +86-21-6875-8025 (Amy Qin)
  • Fax: +86-21-6875-8026
  • Address: Company Name: Shanghai ChemVia Co.,Ltd.
    22F, Huadu Mansion,
    No. 838, Zhangyang Rd,
    Pudong,Shanghai, China
    ZipCode: 200122 null,nullChina
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30653-83-9 PARSALMIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of Benzamide,5-amino-N-butyl-2-(2-propyn-1-yloxy)-
Title: Parsalmide
CAS Registry Number: 30653-83-9
CAS Name: 5-Amino-N-butyl-2-(2-propynyloxy)benzamide
Synonyms: 5-amino-O-propynyl-N-butylsalicylamide; 2-propargyloxy-5-amino-N-butylbenzamide
Manufacturers' Codes: MY-41-6
Trademarks: Sinovial (Irbi); Parsal (Midy)
Molecular Formula: C14H18N2O2
Molecular Weight: 246.30
Percent Composition: C 68.27%, H 7.37%, N 11.37%, O 12.99%
Literature References: Prepn: B. Gradnik et al., DE 2029991; eidem, US 3739030 (1970, 1973 both to Soc. Etude Recher. Sci. Med.). Synthesis and pharmacology: A. Pedrazzoli et al., Boll. Chim. Farm. 115, 125 (1976). Effect on gastric secretion in laboratory animals: G. Bertaccini et al., Farmaco Ed. Prat. 34, 482 (1979). Inhibition of platelet aggregation: R. Fantasia et al., Arzneim.-Forsch. 32, 1312 (1982). Clinical comparison with phenylbutazone, q.v., in management of joint pain: A. Bajardi, S. Fantato, Minerva Med. 67, 3371 (1976); S. Menci et al., ibid. 3403. Series of articles on anti-inflammatory activity, pharmacology and toxicology: Boll. Chim. Farm. 115, 135-230 (1976), C.A. 85, 13981-13986 (1976).
Properties: Crystals from ethanol, mp 83-85°. pKa (aq soln, 20°) 4.6 ±0.03. uv max (abs alcohol): 220 ±1, 327 ±2 nm; (water, pH 2): 284 nm (log e 3.39); (water, pH 8.5): 313 nm (log e 3.40). Very soluble in alcohol, chloroform, acetone, ethyl acetate, dioxane; slightly sol in water. Practically insol in petr ether, cyclohexane.
Melting point: mp 83-85°
pKa: pKa (aq soln, 20°) 4.6 ±0.03
Absorption maximum: uv max (abs alcohol): 220 ±1, 327 ±2 nm; (water, pH 2): 284 nm (log e 3.39); (water, pH 8.5): 313 nm (log e 3.40)
Therap-Cat: Anti-inflammatory; analgesic.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Salicylic Acid Derivatives.