CAS No 306-53-6 , Ethanaminium,2,2'-(methylimino)bis[N-ethyl-N,N-dimethyl-, bromide (1:2)

Name: Ethanaminium,2,2'-(methylimino)bis[N-ethyl-N,N-dimethyl-, bromide (1:2)
Synonyms: Azamethonium bromide; C 9295; Azameton; Pendiomide;Pentamethazene dibromide; Pendoimid;Ammonium,[(methylimino)diethylene]bis[ethyldimethyl-, dibromide (8CI); Pentamin; Ethanaminium,2,2'-(methylimino)bis[N-ethyl-N,N-dimethyl-, dibromide (9CI); Praparat 9295; Ciba 9295; Pendiomide dibromide; Pentamethazine dibromide; Ganlion;Pentamon; Pentamine; Prapar;Pendiomid; Pendiomide bromide; Pentomid; Azamethone;[(Methylimino)diethylene]bis[ethyldimethylammonium bromide] (6CI);3-Methyl-3-azapentane-1,5-bis(ethyldimethylammonium) dibromide;Ethanaminium,2,2'-(methylimino)bis[N-ethyl-N,N-dimethyl-, bromide (1:2);N,N,N',N'-3-Pentamethyl-N,N'-diethyl-3-azapentylene-1,5-diammonium dibromide;
CAS Registry Number:306-53-6
Flash Point: °C
Boiling Point: °Cat760mmHg
Density: g/cm³
Safety Statements: Poison by intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx, NH3, and Br−. See also BROMIDES.
Flash Point: °C
EINECS: 206-186-1
Molecular Weight: 391.31
InChI: InChI=1/C13H33N3.2BrH/c1-8-15(4,5)12-10-14(3)11-13-16(6,7)9-2;;/h8-13H2,1-7H3;2*1H/q+2;;/p-2
Molecular Formula: C13H33 N3 . 2 Br
Molecular Structure:

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References of Ethanaminium,2,2'-(methylimino)bis[N-ethyl-N,N-dimethyl-, bromide (1:2)

Title: Azamethonium Bromide
CAS Registry Number: 306-53-6
CAS Name: 2,2￠-(Methylimino)bis[N-ethyl-N,N-dimethylethanaminium]dibromide
Synonyms: [(methylimino)diethylene]bis[ethyldimethylammonium bromide]; 3-methyl-3-azapentane-1,5-bis(ethyldimethylammonium) dibromide; N,N,N￠,N￠-3-pentamethyl-N,N￠-diethyl-3-azapentylene-1,5-diammonium dibromide; pentamethazene dibromide
Manufacturers' Codes: Pr?parat 9295; Ciba 9295
Trademarks: Pendiomid (Ciba); Azameton; Azamethone; Pentaméthazène
Molecular Formula: C13H33Br2N3
Molecular Weight: 391.23
Percent Composition: C 39.91%, H 8.50%, Br 40.85%, N 10.74%
Literature References: Ganglion blocking agent. Prepd from pentamethyl diethylenetriamine and ethyl bromide: Marxer, Miescher, Helv. Chim. Acta 34, 924 (1951); CH 284212 C.A. 48, 7625 (1954); US 2654785 (1952, 1953 both to Ciba). Pharmacological and toxicity studies: H. J. Bein, R. Meier, Experientia 6, 351 (1950); eidem, Schweiz. Med. Wochenschr. 81, 446 (1951); I. V. Uranov, Farmakol. Toksikol. 21, 110 (1958).
Properties: Prisms or rhombohedra from alcohol + ethyl acetate, mp 212-215°. Freely sol in water. pH of satd aq soln about 6.5. LD50 in mice (mg/kg): 2500 orally; 60 i.v. (Uranov). LD50 in rabbits (mg/kg): 3000 orally; 160 s.c.; 75 i.v. (Bein, Meier, 1951).
Melting point: mp 212-215°
Toxicity data: LD50 in mice (mg/kg): 2500 orally; 60 i.v. (Uranov); LD50 in rabbits (mg/kg): 3000 orally; 160 s.c.; 75 i.v. (Bein, Meier, 1951)
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive; Quaternary Ammonium Compounds.

Status: This monograph has been retired and is no longer subject to revision or update.