CAS No 29218-27-7 , 5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one

Name: 5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one
Synonyms: Toloxatona [INN-Spanish]; Delalande 69276; Toloxatone (INN); Perenum; Toloxatonum [INN-Latin];5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one;Humoryl; 29218-27-7; Toloxatone [INN];
CAS Registry Number:29218-27-7
Transport: 3249
Flash Point: 170.9°C
Boiling Point: 358.9°Cat760mmHg
Density: 1.245g/cm³
Refractive index: 1.57
Safety Statements: RIDADR 3249HazardClass 6.1(b)PackingGroup III
Flash Point: 170.9°C
EINECS: 249-522-2
Molecular Weight: 207.22582
InchiKey: MXUNKHLAEDCYJL-UHFFFAOYSA-N
InChI: InChI=1S/C11H13NO3/c1-8-3-2-4-9(5-8)12-6-10(7-13)15-11(12)14/h2-5,10,
13H,6-7H2,1H3
Molecular Formula: C₁₁H₁₃NO₃
Molecular Structure:

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29218-27-7 TOLOXATONE

Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
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Address: Rm.902 Longyin Plaza,
No. 217 Zhongshan Rd.
(N)Nanjing 210009,China null,nullChina

29218-27-7 Toloxatone

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Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China null,nullChina

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References of 5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one

Title: Toloxatone
CAS Registry Number: 29218-27-7
CAS Name: 5-(Hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone
Synonyms: 5-(hydroxymethyl)-3-m-tolyl-2-oxazolidinone
Manufacturers' Codes: MD-69276
Trademarks: Humoryl (Delalande); Perenum (Delalande)
Molecular Formula: C11H13NO3
Molecular Weight: 207.23
Percent Composition: C 63.75%, H 6.32%, N 6.76%, O 23.16%
Literature References: Reversible monoamine oxidase type A inhibitor. Prepn: C. Fauran et al., DE 2012120; eidem, US 3655687 (1970, 1972 both to Delalande); eidem, Chim. Ther. 8, 324 (1973). Pharmacology: G. Raynaud et al., ibid. 328. Psychopharmacological profile: J.-P. Kan et al., Eur. J. Med. Chem. 12, 13 (1977); H. Giono-Barber et al., Arzneim.-Forsch. 27, 1188 (1977). Pharmacokinetics: M. S. Benedetti et al., ibid. 32, 276 (1982). Metabolism: A. Malnoe, M. S. Benedetti, Xenobiotica 9, 281 (1979). GLC determn in plasma: S. Vajta et al., J. Chromatogr. 274, 139 (1983). Clinical evaluation in panic disorder: G. Perna et al., J. Clin. Psychopharmacol. 14, 414 (1994).
Properties: Crystals from isopropyl alcohol, mp 76°. LD50 orally in mice (mg/kg): 1850 (Fauran); also reported as 1500 (Raynaud).
Melting point: mp 76°
Toxicity data: LD50 orally in mice (mg/kg): 1850 (Fauran); also reported as 1500 (Raynaud)
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Phenyloxazolidinones; Monoamine Oxidase Inhibitor.