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CAS No 28014-46-2 , ESTRADIOL POLYESTER with PHOSPHORIC ACID

  • Name: ESTRADIOL POLYESTER with PHOSPHORIC ACID
  • Synonyms: POLYOESTRIOLPHOSPHATE;oestradiol phosphate polymer;POLYOESTRIOLPHOSPATE;POLYOESTRADIOLPHOSPHATE;ESTRADIOL POLYESTER with PHOSPHORIC ACID ;Polyestradiol;
  • CAS Registry Number:
  • Melting Point: 370.377
  • Flash Point: 209.6°C
  • Boiling Point: 445.9°Cat760mmHg
  • Density: g/cm3
  • Safety Statements: Confirmed carcinogen producing liver tumors. An experimental teratogen. A drug used in cancer treatment. When heated to decomposition it emits toxic fumes of POx. See also ESTRADIOL, ESTERS, POLYMERS, WATER-INSOLUBLE; POLYMERS, WATER-SOLUBLE, and PHOSPHORIC ACID.
  • Flash Point: 209.6°C
  • Molecular Weight: 0
  • InchiKey: DGPHKOYFSODERC-CMZLOHJFSA-N
  • InChI: InChI=1S/C18H24O2.H3O4P/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20;1-5(2,3)4/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3;(H3,1,2,3,4)/t14-,15-,16+,17+,18+;/m1./s1
  • Molecular Formula: [C18H27O6P]n
  • Molecular Structure:CAS No:28014-46-2 ESTRADIOL POLYESTER with PHOSPHORIC ACID

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28014-46-2 Poly(estradiol phosphate)

  • Poly(estradiol phosphate)
  • United States Carbomer, Inc. [Manufacturer]
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References of ESTRADIOL POLYESTER with PHOSPHORIC ACID
Title: Polyestradiol Phosphate
CAS Registry Number: 28014-46-2
CAS Name: Estradiol phosphate polymer
Synonyms: PEP
Trademarks: Estradurin (Kabi)
Literature References: Polymeric ester of phosphoric acid and estradiol. Mol wt ~26,000. Prepn: Diczfalusy, Endocrinology 54, 471 (1954); Fern? et al., Acta Chem. Scand. 12, 1675 (1958); Diczfalusy et al., US 2928849 (1960 to AB Leo). Clinical pharmacology: P. O. Gunnarsson, B. J. Norlén, Prostate 13, 299 (1988). Clinical trial in prostatic carcinoma: J. Aro, ibid. 18, 131 (1991).
Properties: Solid, mp 195-202°. Very sol in aq pyridine; sol in aq alkali; very slightly sol in ethanol, ethanol + water (1:1), water, dioxane, acetone, chloroform. Intrinsic viscosity [h] in 0.25M NaCl soln at pH 7.5 = 0.04.
Melting point: mp 195-202°
Therap-Cat: Antineoplastic (hormonal).
Keywords: Antineoplastic (Hormonal); Estrogens.