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CAS No 26097-80-3 , propan-2-yl N-[2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-yl]carbamate

  • Name: propan-2-yl N-[2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-yl]carbamate
  • Synonyms: propan-2-yl N-[2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-yl]carbamate; Bonlam; Cambenzole; Camdan; NOE [French]; Noviben; Equiben;Novazole; CBDZ; MK 905;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.4g/cm3
  • Refractive index: 1.694
  • Safety Statements: An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx. See also CARBAMATES.
  • Flash Point: °C
  • EINECS: 247-459-5
  • Molecular Weight: 302.35156
  • InchiKey: QZWHWHNCPFEXLL-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H14N4O2S/c1-8(2)20-14(19)16-9-3-4-10-11(5-9)18-13(17-10)12-
    6-21-7-15-12/h3-8H,1-2H3,(H,16,19)(H,17,18)
  • Molecular Formula: C14H14N4O2S
  • Molecular Structure:CAS No:26097-80-3 propan-2-yl N-[2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-yl]carbamate

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References of propan-2-yl N-[2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-yl]carbamate
Title: Cambendazole
CAS Registry Number: 26097-80-3
CAS Name: [2-(4-Thiazolyl)-1H-benzimidazol-5-yl]carbamic acid 1-methylethyl ester
Synonyms: 2-(4-thiazolyl)-5-benzimidazolecarbamate isopropyl ester; 5-isopropoxycarbonylamino-2-(4-thiazolyl)benzimidazole; 5-isopropoxycarbonylaminothiabendazole; isopropyl 2-(4-thiazolyl)-5-benzimidazolecarbamate
Manufacturers' Codes: MK-905
Trademarks: Camvet (Merck & Co.); Noviben (Merck & Co.)
Molecular Formula: C14H14N4O2S
Molecular Weight: 302.35
Percent Composition: C 55.61%, H 4.67%, N 18.53%, O 10.58%, S 10.61%
Literature References: Prepn and activity studies: Hoff, Fisher, ZA 6800351 (1969 to Merck & Co.), C.A. 72, 90461q (1970); Hoff et al., Experientia 26, 550 (1970). Clinical studies with sheep, cattle and swine: Egerton et al., Res. Vet. Sci. 11, 193, 495, 590 (1970).
Properties: Odorless, white crystalline solid, mp 238-240° (dec). Sol in alcohol, dimethylformamide; sparingly sol in acetone; slightly sol in benzene; very slightly sol in 0.1M HCl. Practically insol in isooctane and water (0.02 mg/ml). Stable in acid and base in range of pH 1 to 12. uv max (0.1N HCl): 319, 232 nm (A1%1cm 740, 670).
Melting point: mp 238-240° (dec)
Absorption maximum: uv max (0.1N HCl): 319, 232 nm (A1%1cm 740, 670)
Therap-Cat-Vet: Anthelmintic.