Home > Name List By p > Physalemin(7CI,8CI,9CI)

CAS No 2507-24-6 , Physalemin(7CI,8CI,9CI)

  • Name: Physalemin(7CI,8CI,9CI)
  • Synonyms: Physalaemin;L-Methioninamide, 5-oxo-L-prolyl-L-alanyl-L-a-aspartyl-L-prolyl-L-asparaginyl-L-lysyl-L-phenylalanyl-L-tyrosylglycyl-L-leucyl-;Physalemin(7CI,8CI,9CI);FI 6422;
  • CAS Registry Number:
  • Flash Point: 1008.1°C
  • Boiling Point: 1743.2°Cat760mmHg
  • Density: 1.331g/cm3
  • Refractive index: 1.59
  • Safety Statements: WGK Germany 3
  • Flash Point: 1008.1°C
  • Molecular Weight: 1265.44
  • InChI: InChI=1/C58H84N14O16S/c1-31(2)25-39(54(84)66-36(49(61)79)21-24-89-4)65-47(76)30-62-51(81)40(27-34-15-17-35(73)18-16-34)68-55(85)41(26-33-11-6-5-7-12-33)69-53(83)37(13-8-9-22-59)67-56(86)42(28-45(60)74)70-57(87)44-14-10-23-72(44)58(88)43(29-48(77)78)71-50(80)32(3)63-52(82)38-19-20-46(75)64-38/h5-7,11-12,15-18,31-32,36-44,73H,8-10,13-14,19-30,59H2,1-4H3,(H2,60,74)(H2,61,79)(H,62,81)(H,63,82)(H,64,75)(H,65,76)(H,66,84)(H,67,86)(H,68,85)(H,69,83)(H,70,87)(H,71,80)(H,77,78)
  • Molecular Formula: C58H84N14O16S
  • Molecular Structure:CAS No:2507-24-6 Physalemin(7CI,8CI,9CI)

Related products

Search by region :

Select to

2507-24-6 Physalemin(7CI,8CI,9CI)

Contact Supplier

2507-24-6 330251 PHYSALAEMIN PGLU-ALA-ASP-PRO-ASN-LYS-PHE-TYR-GLY-LEU-MET-NH2

  • Germany chemcube UG [Manufacturer]
  • Tel: +49 (22 08) 7 75 04 06
  • Fax: +49 (22 08) 7 75 02 30 /
    +49 (32 12) 1 00 74 76
  • Address: chemcube UG
    Salierweg 1
    53859 Niederkassel
    Germany null,nullGermany
Contact Supplier

Select to

1/1
References of Physalemin(7CI,8CI,9CI)
Title: Physalaemin
CAS Registry Number: 2507-24-6
CAS Name: Physalemin
Molecular Formula: C58H84N14O16S
Molecular Weight: 1265.44
Percent Composition: C 55.05%, H 6.69%, N 15.50%, O 20.23%, S 2.53%
Literature References: An undecapeptide belonging to the group of proteins named tachykinins. Found in skin of the amphibian Physalaemus fuscumaculatus: Erspamer et al., Experientia 18, 562 (1962). Structure: Erspamer et al., ibid. 20, 489 (1964); Anastasi et al., Arch. Biochem. Biophys. 108, 341 (1964). Synthesis: Bernardi et al., Experientia 20, 490 (1964); Nakamura et al., JP 71 25384 (1971 to Dainippon), C.A. 75, 152083r (1971). Solid-phase synthesis: W. Voelter et al., Tetrahedron 28, 5963 (1972). Biological activities similar to the tachykinins eledoisin and substance P, q.q.v. Exerts a powerful hypotensive action, stimulates salivary secretion, intestinal contraction, and vasodilation. Occurrence in other Physalaemus spp. and pharmacology: G. Bertaccini et al., Br. J. Pharmacol. 25, 363 (1965); G. Bertaccini, Pharmacol. Rev. 28, 127 (1976). Differentiation of physalaemin and substance P: Geipert et al., Arch. Pharmacol. 265, 225 (1969). Immunoreactivity study in human lung small-cell carcinoma: L. H. Lazarus et al., Science 219, 79 (1983).
 
Derivative Type: Trifluoroacetate dihydrate
Molecular Formula: C58H84N14O16S.CF3COOH.2H2O
Molecular Weight: 1415.49
Percent Composition: C 50.91%, H 6.34%, N 13.85%, O 22.61%, S 2.27%, F 4.03%
Properties: Dec 180°. [a]D20 -56° (c = 0.2 in ethanol). uv max: 278 nm (e 1780). Slowly loses activity when incubated in blood. Inactivated by liver and kidney homogenates.
Optical Rotation: [a]D20 -56° (c = 0.2 in ethanol)
Absorption maximum: uv max: 278 nm (e 1780)
 
Derivative Type: Hydrochloride trihydrate
Molecular Formula: C58H84N14O16S.HCl.3H2O
Molecular Weight: 1355.94
Percent Composition: C 51.38%, H 6.76%, N 14.46%, O 22.42%, S 2.36%, Cl 2.61%
Properties: Dec about 185°. [a]D25 -43° (c = 1 in 95% acetic acid).
Optical Rotation: [a]D25 -43° (c = 1 in 95% acetic acid)