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CAS No 24356-94-3 , Algestone Acetophenide

  • Name: Algestone Acetophenide
  • Synonyms: Algestone Acetophenide;-;
  • CAS Registry Number:
  • Melting Point: 150 - 151
  • Flash Point: 246.7°C
  • Boiling Point: 579°Cat760mmHg
  • Density: 1.19g/cm3
  • Refractive index: 1.59
  • Safety Statements: An experimental teratogen. Other experimental reproductive effects. A steroid. When heated to decomposition it emits acrid smoke and fumes. See PROGESTERONE; PROGESTERONE 16,17-ACETONIDE.
  • Hazard Symbols: Xi: Irritant;
  • Flash Point: 246.7°C
  • EINECS: 246-195-8
  • Molecular Weight: 448.6
  • InChI: InChI=1/C29H36O4/c1-18(30)29-25(32-28(4,33-29)19-8-6-5-7-9-19)17-24-22-11-10-20-16-21(31)12-14-26(20,2)23(22)13-15-27(24,29)3/h5-9,16,22-25H,10-15,17H2,1-4H3/t22?,23-,24-,25+,26?,27?,28?,29+/m0/s1
  • Molecular Formula: C29H36O4
  • Molecular Structure:CAS No:24356-94-3 Algestone Acetophenide

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References of Algestone Acetophenide
Title: Algestone Acetophenide
CAS Registry Number: 24356-94-3
CAS Name: [16a(R)]-16,17-[(1-Phenylethylidene)bis(oxy)]pregn-4-ene-3,20-dione
Synonyms: 16a,17-dihydroxypregn-4-ene-3,20-dione cyclic acetal with acetophenone; 16a,17a-dihydroxyprogesterone acetophenide; alphasone acetophenide; P-DHP
Manufacturers' Codes: SQ-15101
Trademarks: Deladroxone (obsolete) (BMS); Droxone (obsolete) (BMS); Neolutin Depositum (Medici)
Molecular Formula: C29H36O4
Molecular Weight: 448.59
Percent Composition: C 77.65%, H 8.09%, O 14.27%
Literature References: Progestogen. Prepn: J. Fried, US 2941997 (1960 to Olin Mathieson); J. Fried et al., Chem. Ind. (London) 1961, 465. Improved prepn: IE 6800457; S. J. Brancato et al., US 3488347 (1968, 1970 both to Smith Kline & French). In estrus synchronization: J. N. Wiltbank et al., J. Anim. Sci. 26, 764 (1967). Clinical evaluations of combination with estradiol enanthate as injectable contraceptive: R. Plesner, Acta Endocrinol. 61, 494 (1969); idem, ibid. 65, 683 (1970); R. Recio et al., Contraception 33, 579 (1986).
Properties: Crystals from 95% ethanol, mp 150-151°. [a]D23 +51° (CHCl3). Stable to boiling mineral acids; readily cleaved by warming with formic acid, with subsequent deformylation.
Melting point: mp 150-151°
Optical Rotation: [a]D23 +51° (CHCl3)
Therap-Cat: Antiacne.
Keywords: Antiacne.