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CAS No 23964-58-1 , methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate Search by region : China

  • Name: methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate
  • Synonyms: Articaina [INN-Spanish];methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate; Hoe-045;Articaine; Carticaine; Articainum [INN-Latin]; 23964-58-1;
  • CAS Registry Number:
  • Flash Point: 220.3 ºC
  • Boiling Point: 440.6 ºC at 760 mmHg
  • Density: 1.178 g/cm3
  • Refractive index: 1.556
  • Flash Point: 220.3 ºC
  • EINECS: 245-957-7
  • Molecular Weight: 284.3745
  • InchiKey: QTGIAADRBBLJGA-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H20N2O3S/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-
    4/h7,9,14H,5-6H2,1-4H3,(H,15,16)
  • Molecular Formula: C13H20N2O3S
  • Molecular Structure:CAS No:23964-58-1 methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate

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23964-58-1 Articaine

  • Articaine Synonyms: methyl 4-methyl-3-(2-propylaminopropanoylamino)thiophene-2-carboxylate;Articaine;Articaine HCL;4-Methyl-3-[2-[propylamino] propionamido]-2-thiophenecarboxylic acid, methyl ester;Carticaine;40045;4-Methyl-3-[[1-oxo-2-(propylamino)p...
  • Min. Order: 10000
  • FOB Price: USD1 - 2 /
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References of methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate
Title: Carticaine
CAS Registry Number: 23964-58-1
CAS Name: 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester
Synonyms: 3-propylamino-a-propionylamino-2-carbomethoxy-4-methylthiophene; methyl 4-methyl-3-(2-propylaminopropionamido)thiophene-2-carboxylate; articaine
Molecular Formula: C13H20N2O3S
Molecular Weight: 284.37
Percent Composition: C 54.91%, H 7.09%, N 9.85%, O 16.88%, S 11.28%
Literature References: Prepn: H. Ruschig et al., ZA 6804265; eidem, US 3855243 (1969, 1974 both to Farbwerke Hoechst). Pharmacological studies: R. Muschaweck, R. Rippel, Prakt. Anaesth. 9, 135 (1974); H. Hofer et al., ibid. 157; A. Den Hertog, Eur. J. Pharmacol. 26, 175 (1974). Toxicity studies: C. Baeder et al., Prakt. Anaesth. 9, 147 (1974). Mechanism of action: U. Borchard, H. Drouin, Eur. J. Pharmacol. 62, 73 (1980). Review: H. Schneider, Schweiz. Monatsschr. Zahnheilkd. 86, 1188-1194 (1976).
Properties: bp0.3 162-167°.
Boiling point: bp0.3 162-167°
 
Derivative Type: Hydrochloride
CAS Registry Number: 23964-57-0
Manufacturers' Codes: HOE-045; HOE-40045
Trademarks: Ultracain (HMR)
Molecular Formula: C13H20N2O3S.HCl
Molecular Weight: 320.84
Percent Composition: C 48.67%, H 6.60%, N 8.73%, O 14.96%, S 9.99%, Cl 11.05%
Properties: White, fine crystals, mp 177-178°. LD50 i.v. in mice: 37 mg/kg (Muschaweck, Rippel).
Melting point: mp 177-178°
Toxicity data: LD50 i.v. in mice: 37 mg/kg (Muschaweck, Rippel)
 
Therap-Cat: Anesthetic (local).
Keywords: Anesthetic (Local).