Home > Name List By n > N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1- amine China

CAS No 226256-56-0 , N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-
amine Search by region : China

  • Name: N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-
    amine
  • Synonyms: CHEBI:48390; Cinacalcet [INN];226256-56-0; Cinacalcet (USAN); HSDB 7318; AMG073;N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-
    amine; AMG 073; AC1L4G5X; UNII-UAZ6V7728S;
  • CAS Registry Number:
  • Flash Point: 220.5 ºC
  • Boiling Point: 440.9 ºC at 760mmHg
  • Density: 1.154 g/cm3
  • Refractive index: 1.563
  • Flash Point: 220.5 ºC
  • Molecular Weight: 357.41199
  • InchiKey: VDHAWDNDOKGFTD-MRXNPFEDSA-N
  • InChI: InChI=1S/C22H22F3N/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-
    4-11-19(15-17)22(23,24)25/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3/t16-/m1/s1
  • Molecular Formula: C22H22F3N
  • Molecular Structure:CAS No:226256-56-0 N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-<br />amine

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References of N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-
amine
Title: Cinacalcet
CAS Registry Number: 226256-56-0
CAS Name: (aR)-a-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-napthalenemethanamine
Synonyms: (R)-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-(1-napthyl)ethylamine
Manufacturers' Codes: AMG-073; KRN-1493
Molecular Formula: C22H22F3N
Molecular Weight: 357.41
Percent Composition: C 73.93%, H 6.20%, F 15.95%, N 3.92%
Literature References: Calcimimetic. Prepn: B. C. Van Wagenen et al., US 6211244 (2001 to NPS Pharmaceuticals). Review of pharmacology and mechanism of action: M. Wada, N. Nagano, Nephrol. Dial. Transplant. 18, Suppl. 3, iii13-iii17 (2003); of clinical development: N. Franceschini et al., Expert Opin. Invest. Drugs 12, 1413-1421 (2003). Clinical trial in secondary hyperparathyroidism: G. A. Block et al., N. Engl. J. Med. 350, 1516 (2004).
 
Derivative Type: Hydrochloride
CAS Registry Number: 364782-34-3
Trademarks: Mimpara (Amgen); Sensipar (Amgen)
Molecular Formula: C22H22F3N.HCl
Molecular Weight: 393.87
Percent Composition: C 67.09%, H 5.89%, F 14.47%, N 3.56%, Cl 9.00%
Properties: White to off-white, crystalline solid. Sol in methanol, 95% ethanol; slightly sol in water.
 
Therap-Cat: Antihyperparathyroid.
Keywords: Antihyperparathyroid.