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CAS No 21730-16-5 , N,11-dimethyl-5,6-dihydrobenzo[b][1]benzazepin-5-amine

  • Name: N,11-dimethyl-5,6-dihydrobenzo[b][1]benzazepin-5-amine
  • Synonyms: Metapraminum [Latin]; Metapramina [Spanish];Metapramine [INN];N,11-dimethyl-5,6-dihydrobenzo[b][1]benzazepin-5-amine; 21730-16-5; Metapramina [INN-Spanish]; Metapraminum [INN-Latin];
  • CAS Registry Number:
  • Flash Point: 140.7°C
  • Boiling Point: 350.8°Cat760mmHg
  • Density: 1.12g/cm3
  • Refractive index: 1.633
  • Flash Point: 140.7°C
  • Molecular Weight: 238.32752
  • InchiKey: YXVZOBVWVRFPTE-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H18N2/c1-17-14-11-12-7-3-5-9-15(12)18(2)16-10-6-4-8-13(14)
    16/h3-10,14,17H,11H2,1-2H3
  • Molecular Formula: C16H18N2
  • Molecular Structure:CAS No:21730-16-5 N,11-dimethyl-5,6-dihydrobenzo[b][1]benzazepin-5-amine

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21730-16-5 Metapramine

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21730-16-5 METAPRAMINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of N,11-dimethyl-5,6-dihydrobenzo[b][1]benzazepin-5-amine
Title: Metapramine
CAS Registry Number: 21730-16-5
CAS Name: 10,11-Dihydro-N,5-dimethyl-5H-dibenz[b,f]azepin-10-amine
Synonyms: 10,11-dihydro-5-methyl-10-(methylamino)-5H-dibenz[b,f]azepine
Manufacturers' Codes: RP-19560
Trademarks: Timaxel (Rh>e-Poulenc)
Molecular Formula: C16H18N2
Molecular Weight: 238.33
Percent Composition: C 80.63%, H 7.61%, N 11.75%
Literature References: Psychotropic agent, related structurally to imipramine, q.v. Prepn: J. C. Fouche, C. G. A. Gueremy, ZA 6800345 corresp to US 3622565 (1968, 1971 both to Rhone-Poulenc). Determn in plasma by GC: A. R. Viala et al., Anal. Chem. 49, 2354 (1977). HPLC method: J. P. Sommadossi et al., J. Chromatogr. 228, 205 (1982). Pharmacological and clinical effects: P. Dick, Encephale 4, 41 (1978). Clinical studies: L. F. Gayral et al., ibid. 365; E. J. Caille, J.-P. Brun, Psychol. Med. 13, 1879 (1981). Biotransformation in animals and man: B. Decouvelaere et al., Therapie 37, 249 (1982).
 
Derivative Type: Hydrochloride
Molecular Formula: C16H19ClN2
Molecular Weight: 274.79
Percent Composition: C 69.93%, H 6.97%, Cl 12.90%, N 10.19%
Properties: Crystals from isopropanol + ether, mp 238-240°. Injectable formulation. The fumarate is used for tablet formulations.
Melting point: mp 238-240°
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tricyclics.