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CAS No 214745-43-4 , Efalizumab

  • Name: Efalizumab
  • Synonyms: Efalizumab;
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214745-43-4 Efalizumab

  • Efalizumab
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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214745-43-4 EFALIZUMABUM;

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of Efalizumab
Title: Efalizumab
CAS Registry Number: 214745-43-4
CAS Name: Anti-(human CD11a (antigen)) immunoglobulin G1 (human-mouse monoclonal hu1124 g1-chain) disulfide with human-mouse monoclonal hu1124 light chain, dimer
Synonyms: hu1124
Trademarks: Raptiva (Genentech); Xanelim (Genentech)
Literature References: Humanized monoclonal IgG1 antibody directed against the CD11a subunit of lymphocyte function-associated antigen-1 (LFA-1). Inhibits lymphocyte activation, migration and adhesion to endothelial cells. Prepn: P. M. Jardieu, L. G. Presta, WO 9823761; eidem, US 6037454 (1998, 2000 both to Genentech); W. A. Werther et al., J. Immunol. 157, 4986 (1996). Clinical pharmacokinetics: R. J. Bauer et al., J. Pharmacokinet. Biopharm. 27, 397 (1999). Clinical study in psoriasis: M. Lebwohl et al., N. Engl. J. Med. 349, 2004 (2003). Review of pharmacology and therapeutic potential: R. L. Dedrick et al., Transplant Immunol. 9, 181-186 (2002); J. C. Cather et al., Expert Opin. Biol. Ther. 3, 361-370 (2003); of use in chronic psoriasis: J. C. Cather, A. Menter, Expert Opin. Biol. Ther. 5, 393-403 (2005).
Therap-Cat: Antipsoriatic; immunosuppressant.
Keywords: Antipsoriatic.