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CAS No 2139-47-1 , N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)pyridine-3-carboxamide

  • Name: N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)pyridine-3-carboxamide
  • Synonyms: Nicophezon; Nicophesone;N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)pyridine-3-carboxamide; Phenicazone; Nicotazone; Niapyrin;Nicofesone; Nicazane; Nicoreumal; Nicodone;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.33g/cm3
  • Refractive index: 1.671
  • Safety Statements:
    WGK Germany 2
    RTECS QS4005000
  • Flash Point: °C
  • EINECS: 218-387-1
  • Molecular Weight: 308.33454
  • InchiKey: BRZANEXCSZCZCI-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H16N4O2/c1-12-15(19-16(22)13-7-6-10-18-11-13)17(23)21(20(12)
    2)14-8-4-3-5-9-14/h3-11H,1-2H3,(H,19,22)
  • Molecular Formula: C17H16N4O2
  • Molecular Structure:CAS No:2139-47-1 N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)pyridine-3-carboxamide

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References of N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)pyridine-3-carboxamide
Title: Nifenazone
CAS Registry Number: 2139-47-1
CAS Name: N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-pyridinecarboxamide
Synonyms: N-antipyrinylnicotinamide; 2,3-dimethyl-1-phenyl-4-(3-pyridinecarboxamido)-5-pyrazolone; 2,3-dimethyl-4-nicotinamido-1-phenyl-5-pyrazolone; 4-nicotinamido-1,5-dimethyl-2-phenyl-3-pyrazolone; 4-(N-nicotinoylamino)-1-phenyl-2,3-dimethyl-5-pyrazolone; N-nicotinoylaminoantipyrine
Trademarks: Dolongan (S.M.B.); Nicopyron (Trommsdorff); Nikofezon; Niprazina (Italfarmaco); Phenicazone; Reupiron; Thylin
Molecular Formula: C17H16N4O2
Molecular Weight: 308.33
Percent Composition: C 66.22%, H 5.23%, N 18.17%, O 10.38%
Literature References: Prepn: Heid, DE 897407 (1953); Trommsdorff, BE 635597 (1963); Pongraz, Zirm, Monatsh. Chem. 88, 330 (1957); Zorn, Schmidt, Pharmazie 12, 396 (1957).
Properties: Crystals from alc, mp 252-253° (also reported as mp 256-258°). Sparingly sol in water, acetone, ethyl acetate, ether; sol in hot water, alcohol, chloroform, dil acids.
Melting point: mp 252-253° (also reported as mp 256-258°)
Therap-Cat: Analgesic, antipyretic.
Keywords: Analgesic (Non-Narcotic); Antipyretic.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.