Home > Name List By 8 > 8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2, 6-dione Germany

CAS No 2016-63-9 , 8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,
6-dione Search by region : Germany

  • Name: 8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,
    6-dione
  • Synonyms: 2016-63-9;8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,
    6-dione; Bamifyllinum [INN-Latin]; Bamifylline [INN:BAN]; Bamifilina [INN-Spanish];Bamifyllin;
  • CAS Registry Number:
  • Flash Point: 328.1 ºC
  • Boiling Point: 619 ºC at 760 mmHg
  • Density: 1.25
  • Refractive index: 1.623
  • Flash Point: 328.1 ºC
  • Molecular Weight: 385.46008
  • InchiKey: VVUYEFBRTFASAH-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H27N5O3/c1-4-24(12-13-26)10-11-25-16(14-15-8-6-5-7-9-15)21-
    18-17(25)19(27)23(3)20(28)22(18)2/h5-9,26H,4,10-14H2,1-3H3
  • Molecular Formula: C20H27N5O3
  • Molecular Structure:CAS No:2016-63-9 8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,<br />6-dione

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2016-63-9 Bamifylline

  • Bamifylline
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2016-63-9 Bamifylline

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References of 8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,
6-dione
Title: Bamifylline
CAS Registry Number: 2016-63-9
CAS Name: 7-[2-[Ethyl(2-hydroxyethyl)amino]ethyl]-3,7-dihydro-1,3-dimethyl-8-(phenylmethyl)-1H-purine-2,6-dione
Synonyms: 8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]theophylline; 8-benzyl-7-[N-ethyl-N-(b-hydroxyethyl)aminoethyl]theophylline; benzetamophylline; bamiphylline
Manufacturers' Codes: 8102 CB
Molecular Formula: C20H27N5O3
Molecular Weight: 385.46
Percent Composition: C 62.32%, H 7.06%, N 18.17%, O 12.45%
Literature References: Prepn: BE 602888 (1961 to Christiaens), C.A. 56, 5981c (1962). Pharmacology: Georges et al., Therapie 17, 211 (1962). Metabolism: Dodion et al., Arzneim.-Forsch. 19, 785 (1969). Toxicological studies: Georges et al., ibid. 18, 460 (1968).
Properties: Crystals, mp 80-80.5°.
Melting point: mp 80-80.5°
 
Derivative Type: Hydrochloride
CAS Registry Number: 20684-06-4
Manufacturers' Codes: AC-3810; BAX-2739Z
Trademarks: Briofil (Alfa); Trentadil (Evans)
Molecular Formula: C20H27N5O3.HCl
Molecular Weight: 421.92
Percent Composition: C 56.93%, H 6.69%, N 16.60%, O 11.38%, Cl 8.40%
Properties: Crystals, mp 185-186°. LD50 in mice, rats (mg/kg): 246, 1139 orally; 89, 131 i.p.; 67, 65 i.v. (Georges).
Melting point: mp 185-186°
Toxicity data: LD50 in mice, rats (mg/kg): 246, 1139 orally; 89, 131 i.p.; 67, 65 i.v. (Georges)
 
Therap-Cat: Bronchodilator.
Keywords: Bronchodilator; Xanthine Derivatives.