Title: Diponium Bromide
CAS Registry Number: 2001-81-2
CAS Name: 2-[(Dicyclopentylacetyl)oxy]-
N,N,N-triethylethanaminium bromide
Synonyms: triethyl(2-hydroxyethyl)ammonium bromide dicyclopentylacetate; diethylaminoethyl a,a-dicyclopentylacetate ethobromide; dicyclopentylacetic acid b-diethylaminoethyl ester ethobromide; dipenine bromide
Manufacturers' Codes: SA-267
Trademarks: Unospaston (Siegfried)
Molecular Formula: C20H38BrNO2
Molecular Weight: 404.43
Percent Composition: C 59.40%, H 9.47%, Br 19.76%, N 3.46%, O 7.91%
Literature References: Prepn: Barrelet
et al., Ind. Chim. Belge Suppl. 2, 428 (1959);
eidem, CH 344054 (1960 to Siegfried),
C.A. 55, 418b (1961). Pharmacology: G. Stille,
Arzneim.-Forsch. 10, 911 (1960); G. H?usler, U. Jahn,
ibid. 15, 878 (1965).
Properties: Crystals, mp 185-186°. Freely sol in water. LD50 in mice (mg/kg): 570 orally; 88 i.p.; 6.2 i.v. (Stille); in rats (mg/kg): 6.6 i.v.; 780 orally (H?usler, Jahn).
Melting point: mp 185-186°
Toxicity data: LD50 in mice (mg/kg): 570 orally; 88 i.p.; 6.2 i.v. (Stille); in rats (mg/kg): 6.6 i.v.; 780 orally (H?usler, Jahn)
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic.
Status: This monograph has been retired and is no longer subject to revision or update.