Home > Name List By 5 > 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione,21-(acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-, (11b,16b)-

CAS No 19888-56-3 , 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione,21-(acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-, (11b,16b)-

  • Name: 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione,21-(acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-, (11b,16b)-
  • Synonyms: D04198;19888-56-3; Fluazacort (USAN/INN); L-6400; CHEMBL2107273; SureCN24693;5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione,21-(acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-, (11b,16b)-;
  • CAS Registry Number:
  • Flash Point: 312.1°C
  • Boiling Point: 592.4°Cat760mmHg
  • Density: 1.43g/cm3
  • Refractive index: 1.642
  • Flash Point: 312.1°C
  • EINECS: 243-400-2
  • Molecular Weight: 459.507203
  • InchiKey: BYZCJOHDXLROEC-RBWIMXSLSA-N
  • InChI: InChI=1S/C25H30FNO6/c1-13-27-25(20(31)12-32-14(2)28)21(33-13)10-18-17-6-
    5-15-9-16(29)7-8-22(15,3)24(17,26)19(30)11-23(18,25)4/h7-9,17-19,21,30H,
    5-6,10-12H2,1-4H3/t17-,18-,19-,21+,22-,23-,24-,25+/m0/s1
  • Molecular Formula: C25H30FNO6
  • Molecular Structure:CAS No:19888-56-3 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione,21-(acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-, (11b,16b)-

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19888-56-3 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione,21-(acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-, (11b,16b)-

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19888-56-3 FLUAZACORT

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione,21-(acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-, (11b,16b)-
Title: Fluazacort
CAS Registry Number: 19888-56-3
CAS Name: (11b,16b)-21-(Acetyloxy)-9-fluoro-11-hydroxy-2￠-methyl-5￠H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione
Synonyms: 9-fluoro-11b,21-dihydroxy-2￠-methyl-5￠bH-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 21-acetate
Manufacturers' Codes: L-6400
Trademarks: Azacortid (Lepetit)
Molecular Formula: C25H30FNO6
Molecular Weight: 459.51
Percent Composition: C 65.35%, H 6.58%, F 4.13%, N 3.05%, O 20.89%
Literature References: Prepn of the 21-hydroxy compound: G. Nathansohn et al., J. Med. Chem. 10, 799 (1967); of the 21-hydroxy and fluazacort: eidem, GB 1119082; eidem, US 3461119 (1968, 1969 to Lepetit); eidem, Steroids 13, 383 (1969). Pharmacological and physico-chemical properties: eidem, ibid. 365. Percutaneous absorption: J. D. Lewis et al., Arzneim.-Forsch. 25, 1646 (1975).
Properties: Crystals from ethanol, mp 252-255°. [a]D +54.8° (c = 0.5 in CHCl3). uv max (methanol): 238-240 nm (E1%1cm 330).
Melting point: mp 252-255°
Optical Rotation: [a]D +54.8° (c = 0.5 in CHCl3)
Absorption maximum: uv max (methanol): 238-240 nm (E1%1cm 330)
Therap-Cat: Anti-inflammatory.
Keywords: Glucocorticoid.