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CAS No 1982-37-2 , 10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine

  • Name: 10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine
  • Synonyms: Metodilazina; Tacryl; Disyncram; Methodilazine; Tacazyl;10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine; Methdilazinum; Methdilazinum [INN-Latin];Tacaryl; Metodilazina [INN-Spanish];
  • CAS Registry Number:
  • Flash Point: 214.1 ºC
  • Boiling Point: 430.4 ºC at 760 mmHg
  • Density: 1.185 g/cm3
  • Safety Statements: Poison by ingestion and intraperitoneal routes. Human systemic effects by ingestion: somnolence, dyspnea and gastrointestinal changes. When heated to decomposition it emits very toxic fumes of SOx and NOx.
  • Flash Point: 214.1 ºC
  • EINECS: 217-841-6
  • Molecular Weight: 296.4298
  • InchiKey: HTMIBDQKFHUPSX-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H20N2S/c1-19-11-10-14(12-19)13-20-15-6-2-4-8-17(15)21-18-9-
    5-3-7-16(18)20/h2-9,14H,10-13H2,1H3
  • Molecular Formula: C18H20N2S
  • Molecular Structure:CAS No:1982-37-2 10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine

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1982-37-2 Methdilazine

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1982-37-2 METHDILAZINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
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References of 10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine
Title: Methdilazine
CAS Registry Number: 1982-37-2
CAS Name: 10-[(1-Methyl-3-pyrrolidinyl)methyl]-10H-phenothiazine
Molecular Formula: C18H20N2S
Molecular Weight: 296.43
Percent Composition: C 72.93%, H 6.80%, N 9.45%, S 10.82%
Literature References: Prepn: Feldkamp, Wu, US 2945855 (1960 to Mead Johnson). Toxicity data: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: Crystals, mp 87-88°.
Melting point: mp 87-88°
 
Derivative Type: Hydrochloride
CAS Registry Number: 1229-35-2
Trademarks: Dilosyn; Disyncran; Tacaryl (Westwood)
Molecular Formula: C18H20N2S.HCl
Molecular Weight: 332.89
Percent Composition: C 64.94%, H 6.36%, N 8.42%, S 9.63%, Cl 10.65%
Properties: Crystals from isopropyl alc, mp 187.5-189°. LD50 orally in rats: 320 mg/kg (Goldenthal).
Melting point: mp 187.5-189°
Toxicity data: LD50 orally in rats: 320 mg/kg (Goldenthal)
 
Therap-Cat: Antipruritic.
Keywords: Antipruritic.