Title: Cyproquinate
CAS Registry Number: 19485-08-6
CAS Name: 6,7-Bis(cyclopropylmethoxy)-4-hydroxy-3-quinolinecarboxylic acid ethyl ester
Synonyms: ethyl 6,7-bis(cyclopropylmethoxy)-4-hydroxyquinoline-3-carboxylate; cyproquinidate; cyproxyquine
Manufacturers' Codes: Su-18137
Trademarks: Coxytrol (Squibb)
Molecular Formula: C20H23NO5
Molecular Weight: 357.40
Percent Composition: C 67.21%, H 6.49%, N 3.92%, O 22.38%
Literature References: Prepn by ring closure of corresp dialkyl (alkoxyphenylamino)methylenemalonates: Mizzoni
et al., Experientia 24, 1188 (1968); Mizzoni, DeStevens,
ZA 6705655 (1968 to Ciba),
C.A. 70, 47316t (1969). Review of structure and biology: Mizzoni
et al., J. Med. Chem. 13, 870 (1970).
Properties: Crystals from DMF, mp 288-288.5° (dec).
Melting point: mp 288-288.5° (dec)
Therap-Cat-Vet: Coccidiostat.
Status: This monograph has been retired and is no longer subject to revision or update.