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CAS No 1882-26-4 , [6-(methylcarbamoyloxymethyl)pyridin-2-yl]methyl N-methylcarbamate

  • Name: [6-(methylcarbamoyloxymethyl)pyridin-2-yl]methyl N-methylcarbamate
  • Synonyms: Parmidine; pyridinol carbamate; Anginine;Pyricarbate; Sospitan 500;[6-(methylcarbamoyloxymethyl)pyridin-2-yl]methyl N-methylcarbamate; Parmidine R; Angioxine; Colesterinex; Anginin; Prodectin;
  • CAS Registry Number:
  • Flash Point: 220.2°C
  • Boiling Point: 440.5°Cat760mmHg
  • Density: 1.229g/cm3
  • Refractive index: 1.528
  • Safety Statements: Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES and ESTERS.
  • Flash Point: 220.2°C
  • EINECS: 217-538-9
  • Molecular Weight: 253.2545
  • InchiKey: YEKQSSHBERGOJK-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H15N3O4/c1-12-10(15)17-6-8-4-3-5-9(14-8)7-18-11(16)13-2/h3-
    5H,6-7H2,1-2H3,(H,12,15)(H,13,16)
  • Molecular Formula: C11H15N3O4
  • Molecular Structure:CAS No:1882-26-4 [6-(methylcarbamoyloxymethyl)pyridin-2-yl]methyl N-methylcarbamate

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1882-26-4 PYRICARBATE

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References of [6-(methylcarbamoyloxymethyl)pyridin-2-yl]methyl N-methylcarbamate
Title: Pyridinol Carbamate
CAS Registry Number: 1882-26-4
CAS Name: 2,6-Pyridinedimethanol bis(methylcarbamate) (ester)
Synonyms: 2,6-pyridinylenebis[methyl-N-methylcarbamate]; pyricarbate
Manufacturers' Codes: H-3749
Trademarks: Anginin (Banyu); Angioxine (Roussel Diamant); Aterosan (Aanderson); Atover (Recordati); Cicloven (AGIPS); Colesterinex (Galenica); Duvaline (Almirall); Movecil (Farmitalia); Prodectin (Gedeon Richter); Ravenil (Caber); Sospitan (Kali-Chemie); Vasagin (Salus); Vasocil (Magis); Vasoverin (Banyu)
Molecular Formula: C11H15N3O4
Molecular Weight: 253.25
Percent Composition: C 52.17%, H 5.97%, N 16.59%, O 25.27%
Literature References: Prepd by the reaction of methylamine with 2,6-pyridinedimethanol bis[phenylcarbonate] in methanol: Matsumoto, JP 66 22185 (1966 to Banyu), C.A. 66, 75907x (1967). Pharmacology and clinical evaluation: T. Shimamoto et al., Am. Heart J. 71, 297 (1966). Metabolism: Mallein et al., Therapie 28, 115 (1973). Effects on lipid metabolism and antiatherogenic effect in animals: V. Orbetzova et al., Artery 8, 560 (1980). HPLC determn in biological fluids: A. Suenaga et al., Acta Pharm. Suec. 23, 245 (1986).
Properties: Needles from methanol or acetone, mp 136-137°. uv max (methanol): 264-265 nm. Sparingly sol in cold water; freely sol in hot water. LD50 in mice, rats, rabbits, dogs (mg/kg): 4500, 3400, 5200, 1000 orally (Shimamoto).
Melting point: mp 136-137°
Absorption maximum: uv max (methanol): 264-265 nm
Toxicity data: LD50 in mice, rats, rabbits, dogs (mg/kg): 4500, 3400, 5200, 1000 orally (Shimamoto)
Therap-Cat: Antiarteriosclerotic.
Keywords: Antiatherosclerotic.