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CAS No 18471-20-0 , 2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol

  • Name: 2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol
  • Synonyms: 18471-20-0; Ditazolum;2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol;Ditazole; Ditazole (INN); 2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol; Ditazolo [DCIT]; Ditazolo;
  • CAS Registry Number:
  • Flash Point: 259.5°C
  • Boiling Point: 505.5°Cat760mmHg
  • Density: 1.237g/cm3
  • Refractive index: 1.623
  • Flash Point: 259.5°C
  • EINECS: 242-353-5
  • Molecular Weight: 324.3737
  • InchiKey: UUCMDZWCRNZCOY-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H20N2O3/c22-13-11-21(12-14-23)19-20-17(15-7-3-1-4-8-15)18
    (24-19)16-9-5-2-6-10-16/h1-10,22-23H,11-14H2
  • Molecular Formula: C19H20N2O3
  • Molecular Structure:CAS No:18471-20-0 2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol

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References of 2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol
Title: Ditazol
CAS Registry Number: 18471-20-0
CAS Name: 2,2￠-[(4,5-Diphenyl-2-oxazolyl)imino]bisethanol
Synonyms: N-(4,5-diphenyloxazol-2-yl)diethanolamine; 2-[bis(b-hydroxyethyl)amino]-4,5-diphenyloxazole; 2,2￠-dihydroxy-N-(4,5-diphenyloxazol-2-yl)diethylamine; diethamphenazol
Manufacturers' Codes: S-222
Trademarks: Ageroplas (Serono)
Molecular Formula: C19H20N2O3
Molecular Weight: 324.37
Percent Composition: C 70.35%, H 6.21%, N 8.64%, O 14.80%
Literature References: Prepn: Marchetti et al., J. Med. Chem. 11, 1092 (1968); FR 1538009; E. Marchetti, US 3557135 (1968, 1971 to Ist. Farmacol. Serono). Series of articles on pharmacology and toxicology: L. Caprino et al., Arzneim.-Forsch. 23, 1272-1291 (1973). Metabolism: Marchetti et al., ibid. 1291.
 
Derivative Type: Monohydrate
Properties: Crystals from ethyl ether-petr ether, mp 96-98°. LD50 in mice, rats (mg/kg): 9621, 11380 orally; 3390, 7770 i.p. (Caprino).
Melting point: mp 96-98°
Toxicity data: LD50 in mice, rats (mg/kg): 9621, 11380 orally; 3390, 7770 i.p. (Caprino)
 
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal).