Home > Name List By 2 > 2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1- benzothiophen-6-ol

CAS No 182133-25-1 , 2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-
benzothiophen-6-ol

  • Name: 2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-
    benzothiophen-6-ol
  • Synonyms: 2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-
    benzothiophen-6-ol; SureCN285277; CHEMBL226267; UNII-E569WG6E60; 124708-EP2292576A2; DNC007422; Arzoxifene [INN]; 182133-25-1; AC1L4522;Arzoxifene;
  • CAS Registry Number:
  • Flash Point: 350.8°C
  • Boiling Point: 656.4°Cat760mmHg
  • Density: 1.234
  • Refractive index: 1.635
  • Flash Point: 350.8°C
  • Molecular Weight: 475.59916
  • InchiKey: MCGDSOGUHLTADD-UHFFFAOYSA-N
  • InChI: InChI=1S/C28H29NO4S/c1-31-22-8-5-20(6-9-22)28-27(25-14-7-21(30)19-26(25)
    34-28)33-24-12-10-23(11-13-24)32-18-17-29-15-3-2-4-16-29/h5-14,19,30H,
    2-4,15-18H2,1H3
  • Molecular Formula: C28H29NO4S
  • Molecular Structure:CAS No:182133-25-1 2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-<br />benzothiophen-6-ol

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182133-25-1 Benzo[b]thiophene-6-ol,2-(4-methoxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]-

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182133-25-1 Arzoxifene

  • Arzoxifene, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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References of 2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-
benzothiophen-6-ol
Title: Arzoxifene
CAS Registry Number: 182133-25-1
CAS Name: 2-(4-Methoxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]benzo[b]thiophene-6-ol
Synonyms: [6-hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]2-(4-methoxyphenyl)]benzo[b]thiophene
Manufacturers' Codes: LY-353381
Molecular Formula: C28H29NO4S
Molecular Weight: 475.60
Percent Composition: C 70.71%, H 6.15%, N 2.95%, O 13.46%, S 6.74%
Literature References: Selective estrogen receptor modulator (SERM). Prepn: A. D. Palkowitz, K. J. Thrasher, EP 729956; idem, US 5981765 (1996, 1999 both to Eli Lilly). Pharmacology: M. Sato et al., Endocrinology 139, 4642 (1998); N. Suh et al., Cancer Res. 61, 8412 (2001). Clinical pharmacokinetics: P. N. Münster et al., J. Clin. Oncol. 19, 2002 (2001). Review of clinical evaluations and therapeutic potential: S. Chan, Semin. Oncol. 29, Suppl. 1, 129-133 (2002).
Properties: Solid from hexane, mp 174-176°.
Melting point: mp 174-176°
 
Derivative Type: Hydrochloride
CAS Registry Number: 182133-27-3
Molecular Formula: C28H29NO4S.HCl
Molecular Weight: 512.06
Percent Composition: C 65.68%, H 5.91%, N 2.74%, O 12.50%, S 6.26%, Cl 6.92%
Properties: Crystals from ethanol/ethyl acetate, mp 156-160°.
Melting point: mp 156-160°
 
Therap-Cat: Antineoplastic (hormonal).
Keywords: Antineoplastic (Hormonal); Antiestrogens; Selective Estrogen Receptor Modulator (SERM).