Home > Name List By n > N-[3-chloro-2-[[methyl-(2-morpholin-4-yl-2-oxoethyl)amino]methyl]phenyl] benzamide

CAS No 18053-31-1 , N-[3-chloro-2-[[methyl-(2-morpholin-4-yl-2-oxoethyl)amino]methyl]phenyl]
benzamide

  • Name: N-[3-chloro-2-[[methyl-(2-morpholin-4-yl-2-oxoethyl)amino]methyl]phenyl]
    benzamide
  • Synonyms: Fominobene [INN-French]; Fominobene; Fominobenum; 18053-31-1; Fominoben (INN); fominoben hydrochloride; UNII-TJ2KK6NYJS;Oleptan;N-[3-chloro-2-[[methyl-(2-morpholin-4-yl-2-oxoethyl)amino]methyl]phenyl]
    benzamide;
  • CAS Registry Number:
  • Melting Point: 122.5 - 123
  • Flash Point: 258
  • Boiling Point: 503
  • Density: 1.29 g/cm3 (20 C)
  • Refractive index: 1.622
  • Flash Point: 258
  • EINECS: 241-964-4
  • Molecular Weight: 401.88656
  • InchiKey: KSNNEUZOAFRTDS-UHFFFAOYSA-N
  • InChI: InChI=1S/C21H24ClN3O3/c1-24(15-20(26)25-10-12-28-13-11-25)14-17-18(22)8-
    5-9-19(17)23-21(27)16-6-3-2-4-7-16/h2-9H,10-15H2,1H3,(H,23,27)
  • Molecular Formula: C21H24ClN3O3
  • Molecular Structure:CAS No:18053-31-1 N-[3-chloro-2-[[methyl-(2-morpholin-4-yl-2-oxoethyl)amino]methyl]phenyl]<br />benzamide

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18053-31-1 Fominoben

  • United States LGM Pharma [Manufacturer]
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18053-31-1 FOMINOBEN

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18053-31-1 Benzamide,N-[3-chloro-2-[[methyl[2-(4-morpholinyl)-2-oxoethyl]amino]methyl]phenyl]-

  • China Hangzhou Bettersky pharmtech Co.,Ltd [Manufacturers]
  • Tel: 0086-571-88199336
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  • Address: Dengyun Road No.380, Gongshu District, Hangzhou, Zhejiang province, China Hangzhou,ZhejiangChina
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References of N-[3-chloro-2-[[methyl-(2-morpholin-4-yl-2-oxoethyl)amino]methyl]phenyl]
benzamide
Title: Fominoben
CAS Registry Number: 18053-31-1
CAS Name: N-[3-Chloro-2-[[methyl-[2-(4-morpholinyl)-2-oxoethyl]amino]methyl]phenyl]benzamide
Synonyms: 3￠-chloro-a-[methyl[(morpholinocarbonyl)methyl]amino]-o-benzotoluidide; 3￠-chloro-b-[N-methyl-N-[(morpholinocarbonyl)methyl]aminomethyl]benzanilide
Molecular Formula: C21H24ClN3O3
Molecular Weight: 401.89
Percent Composition: C 62.76%, H 6.02%, Cl 8.82%, N 10.46%, O 11.94%
Literature References: Prepn: FR 1482547; FR Addn. 92488 (1967, 1968 both to Thomae), C.A. 68, 95494e (1968); 72, 21938p (1970); Kruger et al., US 3661903 (1972 to Boehringer, Ing.); eidem, Arzneim.-Forsch. 23, 290 (1973). Series of articles on pharmacology and clinical findings: ibid. 296-375. Metabolism: Zimmer, ibid. 1798. Toxicity data: S. Püschmann, R. Engelhorn, ibid. 296.
Properties: Base, mp 122.5-123°.
Melting point: mp 122.5-123°
 
Derivative Type: Hydrochloride
CAS Registry Number: 24600-36-0
Manufacturers' Codes: PB-89
Trademarks: Finaten (Finadiet); Noleptan (Thomae); Oleptan (Bender); Terion (Lusofarmaco); Tussirama (Serpero)
Molecular Formula: C21H24ClN3O3.HCl
Molecular Weight: 438.35
Percent Composition: C 57.54%, H 5.75%, Cl 16.18%, N 9.59%, O 10.95%
Properties: Crystals, mp 206-208° (dec). Soly in water: 0.1 mg/100 ml; in 0.05N aq tartaric acid: 5 g/100 ml. LD50 in mice, rats (mg/kg): 630, 1201 i.p.; 2200, 1250 orally (Püschmann, Engelhorn).
Melting point: mp 206-208° (dec)
Toxicity data: LD50 in mice, rats (mg/kg): 630, 1201 i.p.; 2200, 1250 orally (Püschmann, Engelhorn)
 
Therap-Cat: Antitussive; respiratory stimulant.
Keywords: Antitussive; Respiratory Stimulant.