Home > Name List By 2 > 2-[4-(4-chlorophenyl)-2-phenyl-1,3-thiazol-5-yl]acetic acid

CAS No 18046-21-4 , 2-[4-(4-chlorophenyl)-2-phenyl-1,3-thiazol-5-yl]acetic acid

  • Name: 2-[4-(4-chlorophenyl)-2-phenyl-1,3-thiazol-5-yl]acetic acid
  • Synonyms: Fentiazaco [INN-Spanish]; BR 700; Fentiazacum [INN-Latin];Donorest; Flogene; Norvedan; MLS003115545;2-[4-(4-chlorophenyl)-2-phenyl-1,3-thiazol-5-yl]acetic acid; 18046-21-4;
  • CAS Registry Number:
  • Melting Point: 162°C
  • Flash Point: 290.2°C
  • Boiling Point: 556.2°Cat760mmHg
  • Density: 1.362g/cm3
  • Refractive index: 1.646
  • Safety Statements: Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. An anti-inflammatory agent. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl−.
  • Flash Point: 290.2°C
  • EINECS: 241-958-1
  • Molecular Weight: 329.80068
  • InchiKey: JIEKMACRVQTPRC-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H12ClNO2S/c18-13-8-6-11(7-9-13)16-14(10-15(20)21)22-17(19-
    16)12-4-2-1-3-5-12/h1-9H,10H2,(H,20,21)
  • Risk Statements: 36/37/38
  • Molecular Formula: C17H12ClNO2S
  • Molecular Structure:CAS No:18046-21-4 2-[4-(4-chlorophenyl)-2-phenyl-1,3-thiazol-5-yl]acetic acid

Related products

Search by region :

Select to

18046-21-4 Fentiazac

  • Fentiazac, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

18046-21-4 Fentiazac

  • Fentiazac, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
Contact Supplier

18046-21-4 FENTIAZAC

  • FENTIAZAC
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
Contact Supplier

18046-21-4 FENTIAZAC

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of 2-[4-(4-chlorophenyl)-2-phenyl-1,3-thiazol-5-yl]acetic acid
Title: Fentiazac
CAS Registry Number: 18046-21-4
CAS Name: 4-(4-Chlorophenyl)-2-phenyl-5-thiazoleacetic acid
Manufacturers' Codes: BR-700; CH-800
Trademarks: Donorest (Wyeth); Flogene (Polifarma); Norvedan (Wyeth)
Molecular Formula: C17H12ClNO2S
Molecular Weight: 329.80
Percent Composition: C 61.91%, H 3.67%, Cl 10.75%, N 4.25%, O 9.70%, S 9.72%
Literature References: Prepn: K. Brown, GB 1145884; idem, US 3476766 (both 1969 to Wyeth). Anti-inflammatory activity: K. Brown et al., Nature 219, 164 (1968). Crystallographic study: R. Destro, Acta Crystallogr. B34, 959 (1978). Absorption: G. Zanolo et al., Boll. Chim. Farm. 119, 209 (1980). Metabolism: S. Fumero et al., Arzneim.-Forsch. 30, 1253 (1980). Pharmacokinetics in humans: M. Quattrini et al., ibid. 31, 1046 (1981). Toxicity study: D. A. Shriver et al., Toxicol. Appl. Pharmacol. 42, 75 (1977). Review of exptl and clinical pharmacology: E. Marmo, Curr. Med. Res. Opin. 6, 53-63 (1979).
Properties: Colorless needles from benzene, mp 161-162°. LD50 in rats, mice (mg/kg): 661, 692 orally (Marmo).
Melting point: mp 161-162°
Toxicity data: LD50 in rats, mice (mg/kg): 661, 692 orally (Marmo)
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Arylacetic Acid Derivatives.