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CAS No 17466-45-4 , Phalloidin

  • Name: Phalloidin
  • Synonyms: EINECS 241-484-5; HSDB 3524; NSC 523214;PHALLOIDIN;Phalloidin; BRN 4347460; 17466-45-4; Phalloidine;
  • CAS Registry Number:
  • Transport: UN 3462 6.1/PG 2
  • Flash Point: 782.6°C
  • Boiling Point: 1370.5°Cat760mmHg
  • Density: 1.51g/cm3
  • Refractive index: 1.683
  • Safety Statements: 22-28-36/37-45
  • Hazard Symbols: T+
  • Flash Point: 782.6°C
  • EINECS: 241-484-5
  • Molecular Weight: 788.86762
  • InchiKey: KPKZJLCSROULON-UHFFFAOYSA-N
  • InChI: InChI=1S/C35H48N8O11S/c1-15-27(47)38-22-10-20-19-7-5-6-8-21(19)41-33(20)
    55-13-24(34(53)43-12-18(46)9-25(43)31(51)37-15)40-32(52)26(17(3)45)42-28
    (48)16(2)36-30(50)23(39-29(22)49)11-35(4,54)14-44/h5-8,15-18,22-26,41,
    44-46,54H,9-14H2,1-4H3,(H,36,50)(H,37,51)(H,38,47)(H,39,49)(H,40,52)(H,
    42,48)
  • Risk Statements: 26/27/28
  • Molecular Formula: C35H48N8O11S
  • Molecular Structure:CAS No:17466-45-4 Phalloidin
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17466-45-4 PHALLOIDIN

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17466-45-4 PHALLOIDIN

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
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References of Phalloidin
Title: Phalloidin
CAS Registry Number: 17466-45-4
Synonyms: Phalloidine
Molecular Formula: C35H48N8O11S
Molecular Weight: 788.87
Percent Composition: C 53.29%, H 6.13%, N 14.20%, O 22.31%, S 4.06%
Literature References: Best known of the toxins isolated from the poisonous green fungus Amanita phalloides (Fr.) Seer., Agaricaceae, known as "the green death cap" or "deadly agaric": Lynen, Wieland, Ann. 533, 93 (1938). Structure: Wieland, Sch?n, ibid. 593, 157 (1955); Wieland, Sch?pf, ibid. 626, 174 (1959); Wieland, Schnabel, ibid. 657, 225 (1962). Differs from amanitin in rapidity of action; at high dose levels, death of mice or rats occurs within 1 or 2 hours. Phalloidin acts by binding actin, q.v., an essential internal structural protein. Ultrastructural pathology: M. A. Russo et al., Am. J. Pathol. 109, 133 (1982). Toxicity study: Vogt, Arch. Exp. Pathol. Pharmakol. 190, 406 (1938). Review of the chemistry and toxicology of the toxins of Amanita phalloides: Wieland, Wieland, Pharmacol. Rev. 11, 87-107 (1959); see also T. Wieland, Fortschr. Chem. Org. Naturst. 25, 214-250 (1967); T. Wieland, H. Faulstich, Crit. Rev. Biochem. 5, 185-260 (1978).
Properties: Hexahydrate, needles from water, mp 280-282°. uv max (water): 295 nm (E1%1cm 0.597). Soly in water (0°): 0.5%; much more sol in hot water; freely sol in methanol, ethanol, butanol, pyridine. LD50 i.m. in albino mice: 3.3 mg/g (Vogt). LD50 i.p. in mice: 2 mg/kg (Wieland, Wieland).
Melting point: mp 280-282°
Absorption maximum: uv max (water): 295 nm (E1%1cm 0.597)
Toxicity data: LD50 i.m. in albino mice: 3.3 mg/g (Vogt); LD50 i.p. in mice: 2 mg/kg (Wieland, Wieland)
CAUTION: See Amanitin.