Title: Cresol Red
CAS Registry Number: 1733-12-6
CAS Name: 4,4¢-(1,1-Dioxido-3
H-2,1-benzoxathiol-3-ylidene)bis[2-methylphenol]
Synonyms: a-hydroxy-a,a-bis(4-hydroxy-
m-tolyl)-
o-toluenesulfonic acid g-sultone;
o-cresolsulfonphthalein
Molecular Formula: C21H18O5S
Molecular Weight: 382.43
Percent Composition: C 65.95%, H 4.74%, O 20.92%, S 8.38%
Literature References: pH sensitive dye. Prepn: M. D. Sohon,
Am. Chem. J. 20, 257 (1898); and properties: H. A. Lubs, W. M. Clark,
J. Wash. Acad. Sci. 6, 481 (1916). Raman spectrum: K. Machida
et al., J. Raman Spectrosc. 8, 172 (1979). Ionization and spectral properties: R. Casula
et al., Talanta 40, 1781 (1993); M. C. Aragoni
et al., ibid. 42, 1157 (1995). Protein dye binding stoichiometry: I. Molnár-Perl
et al., Food Chem. 35, 69 (1990). Use in detection of alkaloids via ion-associates: Z. Skalican
et al., Anal. Lett. 28, 1223 (1995); as pH indicator for emission of NO2 in museum collections: J. Fenn,
Polym. Prepr. 37, 170 (1996); for archived photographic films: J. C. Harthan
et al., Imaging Sci. J. 45, 81 (1997); for microbiological media: L. A. Actis
et al., J. Microbiol. Methods 39, 79 (1999).
Properties: Reddish-brown cryst powder. Sol in alcohol. pH 0.2: red; pH 1.8 yellow; pH 7.2 yellow; pH 8.8 reddish-purple.
Use: Acid-base indicator.