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CAS No 169590-42-5 , 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide

  • Name: 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
  • Synonyms: Celecoxi; Onsenal;Celebrex; Celocoxib; Celebra;4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide; SC 58635; Xilebao; Celecox; 169590-42-5;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 157-159 ºC
  • Boiling Point:
  • Density: 1.43 g/cm3
  • Water Solubility: Insoluble
  • Safety Statements: S22;S24/25;S28;S37/39;
  • Hazard Symbols: UN NO.
  • Molecular Weight: 381.37217
  • InchiKey: RZEKVGVHFLEQIL-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,
    19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
  • Risk Statements: R20/21/22
  • Molecular Formula: C17H14F3N3O2S
  • Molecular Structure:CAS No:169590-42-5 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
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169590-42-5 Celecoxib

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169590-42-5 Celecoxib

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China null,nullChina
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169590-42-5 Celecoxib

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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169590-42-5 Celecoxib

  • China Simag Chemicals [Manufacturer]
  • Tel: +86 592 2680277
  • Fax: +86 592 2680237
  • Address: Simag Chemicals
    A-9D Atlantic sea view city,
    No.9 Hubin West Rd.,
    Xiamen China. null,nullChina
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169590-42-5 Celecoxib

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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169590-42-5 Celecoxib

  • Germany Fox Chemicals GmbH [Manufacturer]
  • Tel: +49.7240.927151/ +49.160.95781845 (Mobile)
  • Fax: +49.7240.927150
  • Address: Fox Chemicals GmbH
    Bockstalstr.10 A
    D-76327 Pfinztal-Germany null,nullGermany
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169590-42-5; 184007-95-2 Celebrex

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169590-42-5 Celecoxib

  • Celecoxib, 99.0%Min
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
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169590-42-5 Celecoxib

  • Celecoxib, 98
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,nullChina
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169590-42-5 Celecoxib

  • Celecoxib, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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References of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Title: Celecoxib
CAS Registry Number: 169590-42-5
CAS Name: 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
Manufacturers' Codes: SC-58635; YM-177
Trademarks: Celebrex (Pfizer); Onsenal (Pfizer)
Molecular Formula: C17H14F3N3O2S
Molecular Weight: 381.37
Percent Composition: C 53.54%, H 3.70%, F 14.94%, N 11.02%, O 8.39%, S 8.41%
Literature References: Selective cyclooxygenase-2 (COX-2) inhibitor. Prepn: J. J. Talley et al., WO 9515316; eidem, US 5466823 (both 1995 to Searle); T. D. Penning et al., J. Med. Chem. 40, 1347 (1997). Clinical pharmacology: P. E. Lipsky, P. C. Isakson, J. Rheumatol. 24, Suppl. 49, 9 (1997). Clinical trials in arthritis: L. S. Simon et al., Arthritis Rheum. 41, 1591 (1998). Evaluation of risk of gastrointestinal toxicity in patients with arthritis: F. E. Silverstein et al., J. Am. Med. Assoc. 284, 1247 (2000). Clinical trial in familial adenomatous polyposis: G. Steinbach et al., N. Engl. J. Med. 342, 1946 (2000).
Properties: Pale yellow solid, mp 157-159°.
Melting point: mp 157-159°
Therap-Cat: Anti-inflammatory. In treatment of familial adenomatous polyposis.
Keywords: Anti-inflammatory (Nonsteroidal); Cyclooxygenase-2 Selective Inhibitor.