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CAS No 163515-35-3 , L-Argininamide,L-methionyl-L-cysteinyl-L-methionyl-L-prolyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-threonyl-L-a-aspartyl-L-histidyl-L-glutaminyl-L-methionyl-L-alanyl-L-arginyl-L-lysyl-L-cysteinyl-L-a-aspartyl-L-a-aspartyl-L-cysteinyl-L-cysteinylglycylglycyl-L-lysylglycyl-L-arginylglycyl-L-lysyl-L-cysteinyl-L-tyrosylglycyl-L-prolyl-L-glutaminyl-L-cysteinyl-L-leucyl-L-cysteinyl-,cyclic (2®

  • Name: L-Argininamide,L-methionyl-L-cysteinyl-L-methionyl-L-prolyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-threonyl-L-a-aspartyl-L-histidyl-L-glutaminyl-L-methionyl-L-alanyl-L-arginyl-L-lysyl-L-cysteinyl-L-a-aspartyl-L-a-aspartyl-L-cysteinyl-L-cysteinylglycylglycyl-L-lysylglycyl-L-arginylglycyl-L-lysyl-L-cysteinyl-L-tyrosylglycyl-L-prolyl-L-glutaminyl-L-cysteinyl-L-leucyl-L-cysteinyl-,cyclic (2®
  • Synonyms: Chlorotoxin;19),(5®L-Argininamide,L-methionyl-L-cysteinyl-L-methionyl-L-prolyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-threonyl-L-a-aspartyl-L-histidyl-L-glutaminyl-L-methionyl-L-alanyl-L-arginyl-L-lysyl-L-cysteinyl-L-a-aspartyl-L-a-aspartyl-L-cysteinyl-L-cysteinylglycylglycyl-L-lysylglycyl-L-arginylglycyl-L-lysyl-L-cysteinyl-L-tyrosylglycyl-L-prolyl-L-glutaminyl-L-cysteinyl-L-leucyl-L-cysteinyl-,cyclic (2®28),(16®Chlorotoxin(Leiurus quinquestriatus) (9CI); 67: PN: WO2006116156 SEQID: 67 claimed protein; 65: PN: WO2008088422 FIGURE: 8 claimedprotein;35)-tetrakis(disulfide);33),(20®
  • CAS Registry Number:
  • Safety Statements:
    WGK Germany 3
  • Molecular Weight: 4004.76
  • Molecular Formula: C158H249 N53 O47 S11

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163515-35-3 Chlorotoxin

  • ChlorotoxinH-Met-Cys-Met-Pro-Cys-Phe-Thr-Thr-Asp-His-Gln-Met-Ala-Arg-Lys-Cys-Asp-Asp-Cys-Cys-Gly-Gly-Lys-Gly-Arg-Gly-Lys-Cys-Tyr-Gly-Pro-Gln-Cys-Leu-Cys-Arg-NH2 (Disulfide bonds between Cys2 and Cys19/Cys5 and Cys28/Cys16 and Cys33/Cys20 and Cys35)Cl...
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163515-35-3 CHLOROTOXIN

  • CHLOROTOXIN
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163515-35-3 H-MET-CYS-MET-PRO-CYS-PHE-THR-THR-ASP-HIS-GLN-MET-ALA-ARG-LYS-CYS-ASP-ASP-CYS-CYS-GLY-GLY-LYS-GLY-ARG-GLY-LYS-CYS-TYR-GLY-PRO-GLN-CYS-LEU-CYS-ARG-NH2 , (DISULFIDE BONDS BETWEEN CYS2 AND CYS19/CYS5 AND CYS28/CYS16 AND CYS33/CYS20 AND CYS35) CHLOROTOXIN

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References of L-Argininamide,L-methionyl-L-cysteinyl-L-methionyl-L-prolyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-threonyl-L-a-aspartyl-L-histidyl-L-glutaminyl-L-methionyl-L-alanyl-L-arginyl-L-lysyl-L-cysteinyl-L-a-aspartyl-L-a-aspartyl-L-cysteinyl-L-cysteinylglycylglycyl-L-lysylglycyl-L-arginylglycyl-L-lysyl-L-cysteinyl-L-tyrosylglycyl-L-prolyl-L-glutaminyl-L-cysteinyl-L-leucyl-L-cysteinyl-,cyclic (2®
Title: Chlorotoxin
CAS Registry Number: 163515-35-3
Synonyms: ClTx; Ctx
Literature References: Small neurotoxic peptide (36 amino acids) isolated from the venom of the scorpion, Leiurus quinquestriatus characterized by 4 disulfide linkages. Specific blocker of small conductance chloride channels. Isoln, purification, and characterization: J. A. DeBin et al., Am. J. Physiol. 264, C361 (1993). Solid phase synthesis: J. Najib et al., 3rd Int. Symp. 1993 Innovation Perspect. Solid Phase Synth. Collect. Pap. 1994, 615. NMR and secondary structure: G. Lippens et al., ibid. 583; and solution structure: eidem, Biochemistry 34, 13 (1995). Identification of chloride channel in gliomas: N. Ullrich et al., Neuroscience 83, 1161 (1998); inhibition of glioma cell invasion: J. Deshane et al., J. Biol. Chem. 278, 4135 (2003). Use in cell topography: G. Tobasnick, A. S. G. Curtis, Eur. Cells Materials 2, 49 (2001).
Use: Biochemical probe for voltage-gated chloride channels.