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CAS No 157283-68-6 , Travoprost Search by region : China

  • Name: Travoprost
  • Synonyms: 15(S)-FLU-IPR; (+)-9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER; FLU-IPR; 9ALPHA,11ALPHA,15S-TRIHYDROXY-16(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER; FLUPROSTENOL ISOPROPYL ESTER; 15(S)-FLUPROSTENOL ISOPROPYL ESTER;(+/-)-16-(M-TRIFLUOROMETHYLPHENOXY)TETRANORPROSTAGLANDIN F2; (+)-FLUPROSTENOL ISOPROPYL ESTER;Propan-2-yl (E)-7-[(1R,2S,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate;Travoprost;
  • CAS Registry Number:
  • Transport: UN 1170 3
  • Density: 1.245 g/cm3
  • Refractive index: 1.547
  • Safety Statements: 11-36/37/38,
  • Hazard Symbols: F,Xi:;
  • Molecular Weight: 500.55
  • InChI: InChI=1/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,19,21-24,30-32H,4,6,10-11,15-16H2,1-2H3/b5-3+,13-12+/t19?,21-,22-,23+,24-/m1/s1
  • Risk Statements: 16-26-36,
  • Molecular Formula: C26H35F3O6
  • Molecular Structure:CAS No:157283-68-6 Travoprost

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  • China Xilin Chemical Group Co., Ltd null
  • Tel: +86-(0)-15527136576
  • Fax: +86-(27)-83820093
  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, null,nullChina
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  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
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  • China Shanghai chemrole co.,ltd [Manufacturers]
  • Tel: 021-50278900
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  • Address: No.6,bisheng road ,shanghai ,china null,ShanghaiChina
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157283-68-6 Travoprost

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
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  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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References of Travoprost
Title: Travoprost
CAS Registry Number: 157283-68-6
CAS Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester
Synonyms: (+)-16-[3-(trifluoromethyl)phenoxy]-17,18,19,20-tetranorprostaglandin F2a isopropyl ester; (+)-9a,11a,15-trihydroxy-16-(3-trifluoromethylphenoxy)-17,18,19,20-tetranor-5-cis-13-trans-prostadienoic acid isopropyl ester
Manufacturers' Codes: AL-6221
Trademarks: Travatan (Alcon)
Molecular Formula: C26H35F3O6
Molecular Weight: 500.55
Percent Composition: C 62.39%, H 7.05%, F 11.39%, O 19.18%
Literature References: Selective FP prostaglandin receptor agonist. Isopropyl ester of (+)-fluprostenol, q.v. General prepn (not claimed): J. W. Stjernschantz, EP 364417 (1989 to Pharmacia). Large scale synthesis: L. T. Boulton et al., Org. Process Res. Dev. 6, 138 (2002). Pharmacology: M. R. Hellberg et al., J. Ocul. Pharmacol. Ther. 17, 421 (2001). LC/MS/MS determn in plasma: B. A. McCue et al., J. Pharm. Biomed. Anal. 28, 199 (2002). Ocular hypotensive effects in dogs: A. B. Carvalho et al., Vet. Ophthalmol. 9, 121 (2006). Clinical trial in glaucoma or ocular hypertension: R. L. Fellman et al., Ophthalmology 109, 998 (2002); in combination with timolol: J. S. Schuman et al., Am. J. Ophthalmol. 140, 242-250 (2005).
Properties: Colorless oil. [a]D20 +14.6° (c = 1.0 in methylene chloride). Very sol in acetonitrile, methanol, octanol, chloroform. Practically insol in water.
Optical Rotation: [a]D20 +14.6° (c = 1.0 in methylene chloride)
Therap-Cat: Antiglaucoma.
Therap-Cat-Vet: Antiglaucoma.
Keywords: Antiglaucoma.