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CAS No 15687-41-9 , Oxyfedrine

  • Name: Oxyfedrine
  • Synonyms: Oxyfedrine;(R-(R*,S*))-3-((2-Hydroxy-1-methyl-2-phenylethyl)amino)-1-( 3-methoxyphenyl)-1-propanone;
  • CAS Registry Number:
  • Flash Point: 241.2 °C
  • Boiling Point: 475.2 °C at 760 mmHg
  • Density: 1.122 g/cm3
  • Refractive index: 1.566
  • Flash Point: 241.2 °C
  • Molecular Weight: 313.39
  • InChI: InChI=1/C19H23NO3/c1-14(19(22)15-7-4-3-5-8-15)20-12-11-18(21)16-9-6-10-17(13-16)23-2/h3-10,13-14,19-20,22H,11-12H2,1-2H3/t14-,19-/m0/s1
  • Molecular Formula: C19H23NO3
  • Molecular Structure:CAS No:15687-41-9 Oxyfedrine

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15687-41-9 Oxyfedrine

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15687-41-9 1-Propanone,3-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-(3-methoxyphenyl)-

  • China Shenzhen Happy Fine Chemicals Inc [Manufacturers]
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  • Address: 13N,Sun-Island Building, Dongmen South Rd., Shenzhen, Guangdong shenzhen,GuangdongChina
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15687-41-9 OXYFEDRINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of Oxyfedrine
Title: Oxyfedrine
CAS Registry Number: 15687-41-9
CAS Name: 3-[[(1S,2R)-2-Hydroxy-1-methyl-2-phenylethyl]amino]-1-(3-methoxyphenyl)-1-propanone
Synonyms: L-3-[(b-hydroxy-a-methylphenethyl)amino]-3￠-methoxypropiophenone; L-(1-hydroxy-1-phenyl-2-propylamino)-1-(m-methoxyphenyl)-1-propanone; oxyphedrine
Molecular Formula: C19H23NO3
Molecular Weight: 313.39
Percent Composition: C 72.82%, H 7.40%, N 4.47%, O 15.32%
Literature References: Partial b-adrenergic agonist with coronary vasodilating and positive inotropic effects. Prepn: K. Thiele, BE 630296; idem, US 3225095 (1963, 1965 both to Degussa). K. Thiele et al., Arzneim.-Forsch. 16, 1064 (1966). Absolute configuration determined by circular dichroism: J. Engel et al., Chem. Ztg. 105, 85 (1981). TLC determn: Musumarra, J. Chromatogr. 350, 151 (1985). Pharmacology: H. Hueller et al., Pharmazie 27, 242 (1972). Mode of action: P. Mentz, W. Forster, Arzneim.-Forsch. 34, 1739 (1984); N. Sternitzke, Z. Kardiol. 73, 586 (1984). In prevention of experimental myocardial necrosis in rats: S. D. Seth et al., Arzneim.-Forsch. 34, 678 (1984). Comparison with atenolol, q.v., in angina pectoris: L. Fananapazir, C. Bray, Br. J. Clin. Pharmacol. 20, 405 (1985).
 
Derivative Type: L-Form hydrochloride
CAS Registry Number: 16777-42-7
Manufacturers' Codes: D-563
Trademarks: Ildamen (Viatris); Modacor (Houd?
Molecular Formula: C19H23NO3.HCl
Molecular Weight: 349.85
Percent Composition: C 65.23%, H 6.91%, N 4.00%, O 13.72%, Cl 10.13%
Properties: Crystals from methanol, mp 192-194°. LD50 in mice (mg/kg): 29 i.v. (Hueller).
Melting point: mp 192-194°
Toxicity data: LD50 in mice (mg/kg): 29 i.v. (Hueller)
 
Derivative Type: DL-Form hydrochloride
CAS Registry Number: 16648-69-4
Properties: mp 173-175°. LD50 in mice (mg/kg): 34 i.v. (Hueller).
Melting point: mp 173-175°
Toxicity data: LD50 in mice (mg/kg): 34 i.v. (Hueller)
 
Therap-Cat: Antianginal. Treatment of coronary insufficiency.
Keywords: ?Adrenergic Agonist; Antianginal; Cardiotonic.