Home > Name List By 1 > 1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine

CAS No 15686-83-6 , 1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine

  • Name: 1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine
  • Synonyms: Pyrantel [INN:BAN]; HSDB 3252; Pirantele [DCIT];Pyrequan; Pirantel [INN-Spanish]; Strongid; Pyrantelum [INN-Latin];1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine; 15686-83-6;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 178-179 deg C
  • Flash Point: 150°C
  • Boiling Point: 324.4°Cat760mmHg
  • Density: 1.13g/cm3
  • Water Solubility: SOLVENT
  • Hazard Symbols: UN NO.
  • Flash Point: 150°C
  • EINECS: 239-774-1(Base)244-837-1(Pamoate)
  • Molecular Weight: 206.30726
  • InchiKey: YSAUAVHXTIETRK-AATRIKPKSA-N
  • InChI: InChI=1S/C11H14N2S/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h2,4-6,9H,3,
    7-8H2,1H3/b6-5+
  • Molecular Formula: C11H14N2S
  • Molecular Structure:CAS No:15686-83-6 1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine

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References of 1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine
Title: Pyrantel
CAS Registry Number: 15686-83-6
CAS Name: (E)-1,4,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl)ethenyl]pyrimidine
Molecular Formula: C11H14N2S
Molecular Weight: 206.31
Percent Composition: C 64.04%, H 6.84%, N 13.58%, S 15.54%
Literature References: Prepn: BE 658987 (1965 to Pfizer), C.A. 64, 8192c (1966); Austin et al., Nature 212, 1273 (1966); Kasubrick, McFarland, ZA 6800516; eidem, US 3502661 (1968, 1970 both to Pfizer). Structure-activity studies: McFarland et al., J. Med. Chem. 12, 1066 (1969). Pharmacology and animal trials: Cornwell, Vet. Rec. 79, 590 (1966); Howes, Lynch, J. Parasitol. 53, 1085 (1967); Eyre, J. Pharm. Pharmacol. 22, 26 (1970).
Properties: Crystals from methanol, mp 178-179°.
Melting point: mp 178-179°
 
Derivative Type: Tartrate
CAS Registry Number: 33401-94-4
Manufacturers' Codes: CP-10423-18
Trademarks: Banminth (Pfizer); Strongid (Pfizer)
Molecular Formula: C11H14N2S.C4H6O6
Molecular Weight: 356.39
Percent Composition: C 50.55%, H 5.66%, N 7.86%, S 9.00%, O 26.94%
Properties: White crystals from hot methanol, mp 148-150°. uv max (water): 312 nm (log e 4.27).
Melting point: mp 148-150°
Absorption maximum: uv max (water): 312 nm (log e 4.27)
 
Derivative Type: Pamoate
CAS Registry Number: 22204-24-6
Synonyms: Pyrantel embonate
Manufacturers' Codes: CP-10423-16
Trademarks: Cobantril (Pfizer); Combantrin (Pfizer); Helmex (Infectopharm); Helmintox (Innoth?a); Nemex (Pfizer)
Molecular Formula: C11H14N2S.C23H16O6
Molecular Weight: 594.68
Percent Composition: C 68.67%, H 5.08%, N 4.71%, S 5.39%, O 16.14%
Properties: Tasteless, yellow crystalline powder. Insol in water.
 
Therap-Cat: Anthelmintic (Nematodes).
Therap-Cat-Vet: Anthelmintic (Nematodes).
Keywords: Anthelmintic (Nematodes).