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CAS No 15599-39-0 , [(methylamino-λ

  • Name: [(methylamino-λ
  • Synonyms: Noxyflex S;Noxitiolinum;4-sulfanylidyne)methylamino]methanol; Noxytioline [INN-French]; Noxytiolin; Noxythioline;[(methylamino-λ Noxytiolinum [INN-Latin]; Noxitolina [INN-Spanish]; Gynaflex;
  • CAS Registry Number:
  • Flash Point: 77°C
  • Boiling Point: 203.7°C at 760 mmHg
  • Density: 1.223g/cm3
  • Refractive index: 1.564
  • Flash Point: 77°C
  • EINECS: 239-679-5
  • Molecular Weight: 120.17342
  • InchiKey: BBJPKBLYPSYKMT-UHFFFAOYSA-N
  • InChI: InChI=1S/C3H8N2OS/c1-4-7-3-5-2-6/h4-6H,2H2,1H3
  • Molecular Formula: C3H8N2OS
  • Molecular Structure:CAS No:15599-39-0 [(methylamino-λ

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References of [(methylamino-λ
Title: Noxythiolin
CAS Registry Number: 15599-39-0
CAS Name: N-(Hydroxymethyl)-N￠-methylthiourea
Synonyms: 1-(hydroxymethyl)-3-methyl-2-thiourea; noxytiolin
Trademarks: Noxyflex-S (Geistlich)
Molecular Formula: C3H8N2OS
Molecular Weight: 120.17
Percent Composition: C 29.98%, H 6.71%, N 23.31%, O 13.31%, S 26.68%
Literature References: Prepn: A. Aebi, E. Hafstetter, GB 970414 (1964 to Ed. Geistlich S?hne), C.A. 61, 15981e (1964). Antibacterial activity in vitro: D. Horsfield, Clin. Trials J. 4, 625 (1967); J. I. Blenkharn, J. Pharm. Pharmacol. 42, 589 (1990). Inhibition of bacterial adherence in vitro: S. P. Gorman et al., J. Appl. Bacteriol. 60, 311 (1986). Clinical evaluation in peritonitis: F. Antos, Clin. Trials J. 17, 159 (1980); in urinary tract sepsis: M. A. Jones, A. Hasan, Br. J. Urol. 62, 311 (1988).
Properties: Crystals. mp 88-90°. Sol in water (10% w/v), ethanol (4% w/v). pH of 2.5% soln: 6.31-7.0. LD50 orally in mice: >3 g/kg (Aebi, Hafstetter).
Melting point: mp 88-90°
Toxicity data: LD50 orally in mice: >3 g/kg (Aebi, Hafstetter)
Therap-Cat: Antiseptic.
Keywords: Antiseptic/Disinfectant.