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CAS No 15307-86-5 , 2-[2-(2,6-dichloroanilino)phenyl]acetic acid Search by region : India

  • Name: 2-[2-(2,6-dichloroanilino)phenyl]acetic acid
  • Synonyms: Voltarol;2-[2-(2,6-dichloroanilino)phenyl]acetic acid; Diclofenacum; 15307-86-5; Novapirina; Voltaren;Diclofenac acid; ProSorb-D; dichlofenac; Pennsaid;
  • CAS Registry Number:
  • Transport: HAZARD
  • Melting Point: 156-158 deg C
  • Flash Point: 203 ºC
  • Boiling Point: 412 ºC at 760 mmHg
  • Density: 1.431 g/cm3
  • Refractive index: 1.66
  • Water Solubility: soluble
  • Hazard Symbols: 6.1 (Packing Group: I) UN NO.
  • Flash Point: 203 ºC
  • EINECS: 239-348-5
  • Molecular Weight: 296.14864
  • InchiKey: DCOPUUMXTXDBNB-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13
    (18)19/h1-7,17H,8H2,(H,18,19)
  • Molecular Formula: C14H11Cl2NO2
  • Molecular Structure:CAS No:15307-86-5 2-[2-(2,6-dichloroanilino)phenyl]acetic acid

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15307-86-5 Diclofenac

  • IUPAC NAME-2-(2-(2,6-dichlorophenylamino)phenyl)acetic acid MOLECULAR FORMULA-C14H11Cl2NO2 MOLAR MASS-296.148 g/mol Diclofenac is used to treat pain, inflammatory disorders, and dysmenorrhea
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
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15307-86-5 DICLOFENAC

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  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
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15307-86-5 DICLOFENAC-D6

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
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15307-86-5 Dichlofenac Acid

  • India Shreeji Pharma International [Manufacturers]
  • Tel: +91-265-3019110
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  • Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018, Vadodara,GujaratIndia
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15307-86-5 Diclofenac

  • India Bindu pharmaceticals pvt.ltd [Manufacturers]
  • Tel: +91-40-23151219
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  • Address: HIG-147, 5th Phase, KPHB Colony, Kukatpally, Hyderbad-500072. hyderabad,nullIndia
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References of 2-[2-(2,6-dichloroanilino)phenyl]acetic acid
Title: Diclofenac
CAS Registry Number: 15307-86-5
CAS Name: 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid
Synonyms: [o-(2,6-dichloroanilino)phenyl]acetic acid
Trademarks: Motifene (Sankyo)
Molecular Formula: C14H11Cl2NO2
Molecular Weight: 296.15
Percent Composition: C 56.78%, H 3.74%, Cl 23.94%, N 4.73%, O 10.80%
Literature References: Prepn: NL 6604752; A. Sallmann, R. Pfister, US 3558690 (1966, 1971 both to Geigy). Pharmacology: Renaud, Lecompte, Thromb. Diath. Haemorrh. 24, 577 (1970), C.A. 74, 86215m (1971); Krupp et al., Experientia 29, 450 (1973). HPLC determn in plasma and urine: J. Godbillon et al., J. Chromatogr. 338, 151 (1985). Symposium on pharmacology and clinical experience: Semin. Arthritis Rheum. 15, Suppl. 1, 57-110 (1985); on pharmacology, efficacy and safety: Am. J. Med. 80, Suppl. 4B, 1-87 (1986). Comprehensive description: C. M. Adeyeye, P-K. Li, Anal. Profiles Drug Subs. 19, 123-144 (1990). Review of clinical trials in actinic keratosis: D. C. Peters, R. H. Foster, Drugs Aging 14, 313-319 (1999).
Properties: Crystals from ether-petr ether, mp 156-158°.
Melting point: mp 156-158°
 
Derivative Type: Diethylammonium salt
CAS Registry Number: 78213-16-8
Trademarks: Voltarol (Novartis)
Molecular Formula: C14H11Cl2NO2.C4H11N
Molecular Weight: 369.29
Percent Composition: C 58.54%, H 6.00%, Cl 19.20%, N 7.59%, O 8.66%
 
Derivative Type: Sodium salt
CAS Registry Number: 15307-79-6
Manufacturers' Codes: GP-45840
Trademarks: Allvoran (TAD); Benfofen (Sanofi-Synthelabo); Dealgic (Pharmacia); Deflamat (Sankyo); Delphinac (Riemser); Dicloflex (Dexcel); Diclomax (Provalis); Diclophlogont (Azupharma); Dicloreum (Alfa); Duravolten (Dura); Ecofenac (Ecosol); Effekton (Teofarma); Lexobene (Merckle); Neriodin (Nagase); Novapirina (Novartis); Primofenac (Streuli); Prophenatin (Nipro); Rewodina (AWD); Rhumalgan (Sandoz); Voldal (Novartis); Voltaren (Novartis); Xenid (RPG)
Molecular Formula: C14H10Cl2NNaO2
Molecular Weight: 318.13
Percent Composition: C 52.86%, H 3.17%, Cl 22.29%, N 4.40%, Na 7.23%, O 10.06%
Properties: Crystals from water, mp 283-285°. uv max (methanol) 283 nm (e 1.05 ′ 105); (phosphate buffer, pH 7.2) 276 nm (e 1.01 ′ 105). Soly at 25°C (mg/ml): deionized water (pH 5.2) >9; methanol >24; acetone 6; acetonitrile <1; cyclohexane <1; HCl (pH 1.1) <1; phosphate buffer (pH 7.2) 6. pKa 4. Partition coefficient (N-octanol/aq. buffer): 13.4. LD50 in mice, rats (mg/kg): ~390, 150 orally (Krupp).
Melting point: mp 283-285°
pKa: pKa 4
Log P: Partition coefficient (N-octanol/aq. buffer): 13.4
Absorption maximum: uv max (methanol) 283 nm (e 1.05 ′ 105); (phosphate buffer, pH 7.2) 276 nm (e 1.01 ′ 105)
Toxicity data: LD50 in mice, rats (mg/kg): ~390, 150 orally (Krupp)
 
Derivative Type: Potassium salt
CAS Registry Number: 15307-81-0
Manufacturers' Codes: CGP-45840B
Trademarks: Cataflam (Novartis)
Molecular Formula: C14H10Cl2KNO2
Molecular Weight: 334.24
Percent Composition: C 50.31%, H 3.02%, Cl 21.21%, K 11.70%, N 4.19%, O 9.57%
 
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Arylacetic Acid Derivatives.