Home > Name List By 1 > 1-methyl-5-nitro-2-propan-2-ylimidazole Germany

CAS No 14885-29-1 , 1-methyl-5-nitro-2-propan-2-ylimidazole Search by region : Germany

  • Name: 1-methyl-5-nitro-2-propan-2-ylimidazole
  • Synonyms: Ipronidazol [INN-Spanish]; Ro 07-1554;1-methyl-5-nitro-2-propan-2-ylimidazole; 14885-29-1; Ipronidazolo [DCIT]; 2-Isopropyl-1-methyl-5-nitroimidazole;Ipropran; Ro 7-1554;
  • CAS Registry Number:
  • Flash Point: 140.9°C
  • Boiling Point: 309.3°Cat760mmHg
  • Density: 1.25g/cm3
  • Refractive index: 1.571
  • Safety Statements: Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 140.9°C
  • EINECS: 238-957-3
  • Molecular Weight: 169.18114
  • InchiKey: NTAFJUSDNOSFFY-UHFFFAOYSA-N
  • InChI: InChI=1S/C7H11N3O2/c1-5(2)7-8-4-6(9(7)3)10(11)12/h4-5H,1-3H3
  • Molecular Formula: C7H11N3O2
  • Molecular Structure:CAS No:14885-29-1 1-methyl-5-nitro-2-propan-2-ylimidazole

Related products

Select to

14885-29-1 IPRONIDAZOLE

Contact Supplier

Select to

1/1
References of 1-methyl-5-nitro-2-propan-2-ylimidazole
Title: Ipronidazole
CAS Registry Number: 14885-29-1
CAS Name: 1-Methyl-2-(1-methylethyl)-5-nitro-1H-imidazole
Synonyms: 2-isopropyl-1-methyl-5-nitroimidazole
Manufacturers' Codes: Ro-7-1554
Trademarks: Ipropran (Roche)
Molecular Formula: C7H11N3O2
Molecular Weight: 169.18
Percent Composition: C 49.70%, H 6.55%, N 24.84%, O 18.91%
Literature References: Prepn: GB 1119636; M. Hoffer, M. Mitrovic, US 3634446 (1968, 1972 both to Hoffmann-La Roche); K. Butler, ZA 6607466 (1968 to Pfizer), C.A. 71, 3384e (1969). Structure-activity relationship: K. Butler et al., J. Med. Chem. 10, 891 (1967). Activity studies as an antihistomonal agent: M. Mitrovic et al., Antimicrob. Agents Chemother. 1968, 445; M. Mitrovic, E. G. Schildknecht, Poult. Sci. 49, 86 (1970); as a growth promotant: W. L. Marusich et al., ibid. 98. Toxicity studies: eidem, ibid. 92.
Properties: White plates, mp 60°. LD50 orally in poults: 640 ± 25 mg/kg (Marusich, p 92).
Melting point: mp 60°
Toxicity data: LD50 orally in poults: 640 ± 25 mg/kg (Marusich, p 92)
 
Derivative Type: Hydrochloride
Properties: mp 177-182°. Water-soluble.
Melting point: mp 177-182°
 
Therap-Cat-Vet: Antiprotozoal (Histomonas).