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CAS No 14334-40-8 , Cyclohexanamine,N-(1-methylethyl)-4,4-diphenyl-

  • Name: Cyclohexanamine,N-(1-methylethyl)-4,4-diphenyl-
  • Synonyms: Cyclohexanamine,N-(1-methylethyl)-4,4-diphenyl-; Pramiverin; Pramiverine;Cyclohexylamine,N-isopropyl-4,4-diphenyl- (8CI); Propaminodiphen;
  • CAS Registry Number:
  • Flash Point: 206°C
  • Boiling Point: 406.9°Cat760mmHg
  • Density: 1.01g/cm3
  • Refractive index: 1.571
  • Flash Point: 206°C
  • Molecular Weight: 0
  • InChI: InChI=1/C21H27N/c1-17(2)22-20-13-15-21(16-14-20,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,17,20,22H,13-16H2,1-2H3
  • Molecular Formula: C21H27 N
  • Molecular Structure:CAS No:14334-40-8 Cyclohexanamine,N-(1-methylethyl)-4,4-diphenyl-

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14334-40-8 Cyclohexanamine,N-(1-methylethyl)-4,4-diphenyl-

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References of Cyclohexanamine,N-(1-methylethyl)-4,4-diphenyl-
Title: Pramiverin
CAS Registry Number: 14334-40-8
CAS Name: N-(1-Methylethyl)-4,4-diphenylcyclohexanamine
Synonyms: N-isopropyl-4,4-diphenylcyclohexylamine; pramiverine; primaverine; propaminodiphen
Molecular Formula: C21H27N
Molecular Weight: 293.45
Percent Composition: C 85.95%, H 9.27%, N 4.77%
Literature References: Prepn: NL 6515046; R. Unger et al., US 3376312 (1966, 1968 both to E. Merck). Pharmacology: H. J. Enenkel et al., Arzneim.-Forsch. 26, 690 (1976). Toxicological study: M. Von Eberstein et al., ibid., 703. Series of articles on pharmacology, pharmacokinetics, GC determn, clinical studies: ibid., 686-752. Use in management of labor: G. LoDico et al., Minerva Ginecol. 31, 683 (1979).
Properties: Liq, bp0.05 164-165°; also reported as a solid, mp 70° (Enenkel).
Melting point: mp 70° (Enenkel)
Boiling point: bp0.05 164-165°
 
Derivative Type: Hydrochloride
CAS Registry Number: 14334-41-9
Manufacturers' Codes: EMD-9806; HSP-2986
Trademarks: Monoverin (Merck KGaA); Sistalgin (Merck KGaA)
Molecular Formula: C21H27N.HCl
Molecular Weight: 329.91
Percent Composition: C 76.45%, H 8.55%, N 4.25%, Cl 10.75%
Properties: Off-white crystalline powder, mp 230°; also reported as 234-237° (Enenkel). Soly at 25° (g/100 ml): in water 0.3; in ethanol 4; in chloroform 5. Practically insol in ether. LD50 (after 14 days) in mice, rats (mg/kg): 346, 623 orally; 25, 26 i.v. (Von Eberstein).
Melting point: mp 230°
Toxicity data: LD50 (after 14 days) in mice, rats (mg/kg): 346, 623 orally; 25, 26 i.v. (Von Eberstein)
 
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic.