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CAS No 14293-44-8 , 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide Search by region : India

  • Name: 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide
  • Synonyms: Aquaphor (diuretic);4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide; Diurex (lacer); Xipamidum [INN-Latin]; Aquaphoril; Aquaphor;14293-44-8; Zipix; Diurexan; Xipamid;
  • CAS Registry Number:
  • Melting Point: 255-256 ºC
  • Density: 1.477 g/cm3
  • Refractive index: 1.652
  • EINECS: 238-216-4
  • Molecular Weight: 354.8086
  • InchiKey: MTZBBNMLMNBNJL-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H15ClN2O4S/c1-8-4-3-5-9(2)14(8)18-15(20)10-6-13(23(17,
    21)22)11(16)7-12(10)19/h3-7,19H,1-2H3,(H,18,20)(H2,17,21,22)
  • Molecular Formula: C15H15ClN2O4S
  • Molecular Structure:CAS No:14293-44-8 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide

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References of 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide
Title: Xipamide
CAS Registry Number: 14293-44-8
CAS Name: 4-Chloro-5-sulfamoyl-2￠,6￠-salicyloxylidide
Synonyms: 4-chloro-2￠,6￠-dimethyl-5-sulfamoylsalicylanilide; 4-chloro-5-sulfamylsalicyloyl-2￠,6￠-dimethylanilide
Manufacturers' Codes: Bei-1293
Trademarks: Aquaphor (Lilly); Chronexan (Viatris); Diurexan (Viatris); Lumitens (Solvay)
Molecular Formula: C15H15ClN2O4S
Molecular Weight: 354.81
Percent Composition: C 50.78%, H 4.26%, Cl 9.99%, N 7.90%, O 18.04%, S 9.04%
Literature References: Salicylic acid derivative. Prepn: NL 6607680; Liebenow, US 3567777 (1966, 1970 both to P. Beiersdorf). Clinical studies: O. Hammer, U. Dembowski, Med. Klin. 64, 1862 (1969); R. Fischer, A. Lenhartz, Med. Welt 1970, 270. Review of pharmacology and therapeutic efficacy: B. N. C. Prichard, R. N. Brogden, Drugs 30, 313-332 (1985).
Properties: Crystals from methanol-water, mp 256°.
Melting point: mp 256°
Therap-Cat: Diuretic; antihypertensive.
Keywords: Antihypertensive; Sulfonamide Derivatives; Diuretic; Sulfonamide Derivatives.