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CAS No 142155-43-9 , Ethanamine,N,N-dimethyl-2-[(1-methyl-1H-pyrazol-5-yl)phenylmethoxy]-

  • Name: Ethanamine,N,N-dimethyl-2-[(1-methyl-1H-pyrazol-5-yl)phenylmethoxy]-
  • CAS Registry Number:
  • Flash Point: 175.2°C
  • Boiling Point: 366°Cat760mmHg
  • Density: 1.04g/cm3
  • Refractive index: 1.546
  • Flash Point: 175.2°C
  • Molecular Weight: 0
  • InChI: InChI=1/C15H21N3O/c1-17(2)11-12-19-15(13-7-5-4-6-8-13)14-9-10-16-18(14)3/h4-10,15H,11-12H2,1-3H3/t15-/m1/s1
  • Molecular Formula: C15H21 N3 O
  • Molecular Structure:CAS No:142155-43-9 Ethanamine,N,N-dimethyl-2-[(1-methyl-1H-pyrazol-5-yl)phenylmethoxy]-

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References of Ethanamine,N,N-dimethyl-2-[(1-methyl-1H-pyrazol-5-yl)phenylmethoxy]-
Title: Cizolirtine
CAS Registry Number: 142155-43-9
CAS Name: N,N-Dimethyl-2-[(1-methyl-1H-pyrazol-5-yl)phenylmethoxy]ethanamine
Synonyms: 1-methyl-a-phenyl-O-(2-dimethylaminoethyl)-1H-pyrazole-5-methanol
Manufacturers' Codes: E-3710
Molecular Formula: C15H21N3O
Molecular Weight: 259.35
Percent Composition: C 69.47%, H 8.16%, N 16.20%, O 6.17%
Literature References: Antinociceptive agent that inhibits release of calcitonin gene related peptide and substance P, q.v., from the spinal cord. Prepn: A. Colombo et al., EP 289380; eidem, US 5017596 (1988, 1991 both to Esteve). Prepn of isomers: J. A. Hueso-Rodriguez et al., Bioorg. Med. Chem. Lett. 3, 269 (1993). CE determn of chemical and enantiomeric purity: A. Gómez-Gomar et al., J. Chromatogr. A 950, 257 (2002). Pharmacology: I. Alvarez et al., Methods Find. Exp. Clin. Pharmacol. 22, 211 (2000). Mechanism of action study: S. Ballet et al., Neuropharmacology 40, 578 (2001). Clinical evaluation in chronic neuropathic pain: P. Shembalkar et al., Curr. Med. Res. Opin. 17, 262 (2001); in renal colic: I. Pavlik et al., Curr. Ther. 26, 1061 (2004). Review: N. Monck, Curr. Opin. Invest. Drugs 2, 1269-1272 (2001).
 
Derivative Type: Citrate
CAS Registry Number: 142155-44-0
Manufacturers' Codes: E-4018
Molecular Formula: C15H21N3O.C6H8O7
Molecular Weight: 451.47
Percent Composition: C 55.87%, H 6.47%, N 9.31%, O 28.35%
 
Therap-Cat: Analgesic.
Keywords: Analgesic (Non-Narcotic).