Home > Name List By l > L-Arginine,7,7'-[1,6-hexanediylbis(2,5-dioxo-1,3-pyrrolidinediyl)]bis[D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylgly...

CAS No 140661-97-8 , L-Arginine,7,7'-[1,6-hexanediylbis(2,5-dioxo-1,3-pyrrolidinediyl)]bis[D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-cysteinyl-D-phenylalanyl-L-leucyl-,stereoisomer

  • Name: L-Arginine,7,7'-[1,6-hexanediylbis(2,5-dioxo-1,3-pyrrolidinediyl)]bis[D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-cysteinyl-D-phenylalanyl-L-leucyl-,stereoisomer
  • Synonyms: 140661-97-8;Bradycor;L-Arginine,7,7'-[1,6-hexanediylbis(2,5-dioxo-1,3-pyrrolidinediyl)]bis[D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-cysteinyl-D-phenylalanyl-L-leucyl-,stereoisomer; CP 0127;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.51g/cm3
  • Refractive index: 1.702
  • Flash Point: °C
  • Molecular Weight: 2805.29116
  • InchiKey: JKUYFMHGTOPVMR-BDVDZANVSA-N
  • InChI: InChI=1S/C128H194N40O28S2/c1-71(2)55-85(105(177)155-83(121(193)194)41-
    25-49-147-127(139)140)157-109(181)89(59-75-33-15-9-16-34-75)159-111(183)
    91(161-107(179)87(57-73-29-11-7-12-30-73)151-99(171)65-149-113(185)95-
    61-77(169)67-167(95)117(189)93-43-27-53-163(93)115(187)81(39-23-47-145-
    125(135)136)153-103(175)79(129)37-21-45-143-123(131)132)69-197-97-63-101
    (173)165(119(97)191)51-19-5-6-20-52-166-102(174)64-98(120(166)192)198-
    70-92(112(184)160-90(60-76-35-17-10-18-36-76)110(182)158-86(56-72(3)4)
    106(178)156-84(122(195)196)42-26-50-148-128(141)142)162-108(180)88(58-
    74-31-13-8-14-32-74)152-100(172)66-150-114(186)96-62-78(170)68-168(96)
    118(190)94-44-28-54-164(94)116(188)82(40-24-48-146-126(137)138)154-104
    (176)80(130)38-22-46-144-124(133)134/h7-18,29-36,71-72,77-98,169-170H,
    5-6,19-28,37-70,129-130H2,1-4H3,(H,149,185)(H,150,186)(H,151,171)(H,152,
    172)(H,153,175)(H,154,176)(H,155,177)(H,156,178)(H,157,181)(H,158,
    182)(H,159,183)(H,160,184)(H,161,179)(H,162,180)(H,193,194)(H,195,
    196)(H4,131,132,143)(H4,133,134,144)(H4,135,136,145)(H4,137,138,146)(H4,
    139,140,147)(H4,141,142,148)/t77-,78-,79+,80+,81+,82+,83+,84+,85+,86+,
    87+,88+,89-,90-,91+,92+,93+,94+,95+,96+,97?,98?/m1/s1
  • Molecular Formula: C128H194N40O28S2
  • Molecular Structure:CAS No:140661-97-8 L-Arginine,7,7'-[1,6-hexanediylbis(2,5-dioxo-1,3-pyrrolidinediyl)]bis[D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-cysteinyl-D-phenylalanyl-L-leucyl-,stereoisomer

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140661-97-8 Deltibant

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140661-97-8 DELTIBANT

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References of L-Arginine,7,7'-[1,6-hexanediylbis(2,5-dioxo-1,3-pyrrolidinediyl)]bis[D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-cysteinyl-D-phenylalanyl-L-leucyl-,stereoisomer
Title: Bradycor
CAS Registry Number: 140661-97-8
Manufacturers' Codes: CP-0127
Molecular Formula: C128H194N40O28S2
Molecular Weight: 2805.29
Percent Composition: C 54.80%, H 6.97%, N 19.97%, O 15.97%, S 2.29%
Literature References: Bradykinin antagonist. Dimer of D-Arg0-[Hyp3, Cys6, D-Phe7, Leu8]-bradykinin joined by a bissuccinimidohexane linker via the sulfhydryl moieties of the cysteine residues. Prepn: J. C. Cheronis et al., WO 9217201 (1992 to Cortech); eidem, J. Med. Chem. 35, 1563 (1992). Effect on survival in endotoxin shock in animals: E. T. Whalley et al., Agents Actions Suppl. 38 (3), 413 (1992).
Therap-Cat: In treatment of systemic inflammatory response syndrome.
Keywords: Bradykinin Antagonist.