CAS No 1398-78-3 , colocynthin

Name: colocynthin
Synonyms: alpha-Elaterin 2-D-glucopyranoside;Colocynthin;Coloside A;(4R,9beta,16alpha,23E)-2-(D-glucopyranosyloxy)-16,20-dihydroxy-9,10,14-trimethyl-1,11,22-trioxo-4,9-cyclo-9,10-secocholesta-2,5,23-trien-25-yl acetate;Cueg;Elaterinide;colocynthin;19-Nor-9-beta,10-alpha-lanosta-1,5,23-triene-3,11,22-trione, 2-(beta-D-glucopyranosyloxy)-9-methyl-16-alpha,20,25-trihydroxy-, 25-acetate;Elaterin, 2-beta-glucopyranoside;beta-Glucoside de LA curcurbitaine (E);UNII-6984R18595;
CAS Registry Number:1398-78-3
Flash Point: 266.1°C
Boiling Point: 878°C at 760 mmHg
Density: 1.35g/cm³
Refractive index: 1.602
Flash Point: 266.1°C
EINECS: 215-745-9
Molecular Weight: 718.8276
InChI: InChI=1/C38H54O13/c1-18(40)51-33(2,3)13-12-25(42)38(9,48)30-21(41)15-35(6)24-11-10-19-20(37(24,8)26(43)16-36(30,35)7)14-22(31(47)34(19,4)5)49-32-29(46)28(45)27(44)23(17-39)50-32/h10,12-14,20-21,23-24,27-30,32,39,41,44-46,48H,11,15-17H2,1-9H3/b13-12+/t20-,21-,23-,24+,27-,28+,29-,30+,32?,35+,36-,37+,38+/m1/s1
Molecular Formula: C₃₈H₅₄O₁₃
Molecular Structure:

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1398-78-3 CUCURBITACIN E-2-O-GLUCOSIDE

Cfm Oskar Tropitzsch [Manufacturer]
Tel: +49-9231-9619-0
Fax: +49-9231-9619-60
Address: Cfm Oskar Tropitzsch
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95615 Marktredwitz
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1398-78-3 CUCURBITACIN E-2-O-GLUCOSIDE

Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
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Address: Rm.902 Longyin Plaza,
No. 217 Zhongshan Rd.
(N)Nanjing 210009,China null,nullChina

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References of colocynthin

Title: Colocynthin
CAS Registry Number: 1398-78-3
CAS Name: 25-(Acetyloxy)-2-(b-D-glucopyranosyloxy)-16,20-dihydroxy-9-methyl-19-norlanosta-1,5,23-triene-3,11,22-trione
Synonyms: 2-O-b-D-glucopyranosylcucurbitacin E
Molecular Formula: C38H54O13
Molecular Weight: 718.83
Percent Composition: C 63.49%, H 7.57%, O 28.93%
Literature References: Glucoside from fruit of Citrullus colocynthis Schrad., Cucurbitaceae: Walz, Neues Jahrb. Pharm. 9, 16, 225 (1858); 16, 10 (1861); Henke, Arch. Pharm. 221, 200 (1883); Naylas, Chappel, Pharm. J. 25, 117 (1907); Lavie et al., Acta Univ. Int. Contra Cancerum 15, 177 (1959); Khadem, Rahman, Tetrahedron Lett. 1962, 1137. Other isolns: H. Ripperger, K. Seifert, Tetrahedron 31, 1561 (1975); H. Ripperger, ibid. 32, 1567 (1976). Structure: Khadem, Rahman, J. Chem. Soc. 1963, 4991.
Properties: Yellow crystals, mp 158-160°. [a]D +50° (c = 0.4 in ethanol). uv max: 234-236 nm (log e 4.11). Sol in ethanol, acetone, chloroform; slightly sol in ether, water.
Melting point: mp 158-160°
Optical Rotation: [a]D +50° (c = 0.4 in ethanol)
Absorption maximum: uv max: 234-236 nm (log e 4.11)
Therap-Cat: Cathartic.
Keywords: Laxative/Cathartic.