Home > Name List By a > APTIGANEL HYDROCHLORIDE

CAS No 137159-92-3 , APTIGANEL HYDROCHLORIDE

  • Name: APTIGANEL HYDROCHLORIDE
  • Synonyms: CERESTAT;Aptiganel [inn];Unii-46475lv84i;CNS-1102;N-(3-ETHYLPHENYL)-N-METHYL-N''-1-NAPHTHALENYLGUANIDINE HYDROCHLORIDE;APTIGANEL HYDROCHLORIDE;1-(m-Ethylphenyl)-1-methyl-3-(1-naphthyl)guanidine;Aptiganel hydrochloride, Cerestat, N-(3-Ethylphenyl)-N-methyl-N-1-naphthalenylguanidine hydrochloride;
  • CAS Registry Number:
  • Density: 1.08g/cm3
  • Refractive index: 1.599
  • Safety Statements: 23-24/25
  • Molecular Weight: 303.4
  • InChI: InChI=1/C20H21N3/c1-3-15-8-6-11-17(14-15)23(2)20(21)22-19-13-7-10-16-9-4-5-12-18(16)19/h4-14H,3H2,1-2H3,(H2,21,22)
  • Molecular Formula: C20H21N3
  • Molecular Structure:CAS No:137159-92-3 APTIGANEL HYDROCHLORIDE

Related products

Search by region :

Select to

137159-92-3 Aptiganel

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
Contact Supplier

137159-92-3 Aptiganel

  • Aptiganel, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

Select to

1/1
References of APTIGANEL HYDROCHLORIDE
Title: Aptiganel
CAS Registry Number: 137159-92-3
CAS Name: N-(3-Ethylphenyl)-N-methyl-N￠-1-naphthalenylguanidine
Synonyms: N-(1-naphthyl)-N￠-(3-ethylphenyl)-N￠-methylguanidine; aptaguanal
Molecular Formula: C20H21N3
Molecular Weight: 303.40
Percent Composition: C 79.17%, H 6.98%, N 13.85%
Literature References: Noncompetitive NMDA-receptor antagonist. Prepn: E. Weber, J. F. W. Keana, WO 9112797; eidem, US 5262568 (1991, 1993 both to State of Oregon); N. L. Reddy et al., J. Med. Chem. 37, 260 (1994). Clinical pharmacology and kinetics: K. W. Muir et al., Ann. N.Y. Acad. Sci. 765, 279 (1995). Review of theoretical basis for use in stroke: K. W. Muir, K. R. Lees, Stroke 26, 503-513 (1995). Clinical trial in acute ischemic stroke: G. W. Albers et al., J. Am. Med. Assoc. 286, 2673 (2001).
 
Derivative Type: Hydrochloride
CAS Registry Number: 137160-11-3
Manufacturers' Codes: CNS-1102
Trademarks: Cerestat (Cambridge Neurosci.)
Molecular Formula: C20H21N3.HCl
Molecular Weight: 339.86
Percent Composition: C 70.68%, H 6.52%, N 12.36%, Cl 10.43%
Properties: Off-white needles from ethanol + diethyl ether, mp 223-225°.
Melting point: mp 223-225°
 
Therap-Cat: Neuroprotective.
Keywords: Neuroprotective; NMDA Receptor Antagonist.