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CAS No 135459-90-4 , 3-Thiopheneacetic acid,5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-

  • Name: 3-Thiopheneacetic acid,5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-
  • Synonyms: 3-Thiopheneacetic acid,5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-;Ranelicacid;
  • CAS Registry Number:
  • Flash Point: 424.8°C
  • Boiling Point: 778.8°Cat760mmHg
  • Density: 1.81g/cm3
  • Flash Point: 424.8°C
  • Molecular Weight: 0
  • InChI: InChI=1/C12H10N2O8S.2Sr/c13-2-6-5(1-7(15)16)10(12(21)22)23-11(6)14(3-8(17)18)4-9(19)20;;/h1,3-4H2,(H,15,16)(H,17,18)(H,19,20)(H,21,22);;/q;2*+2/p-4
  • Molecular Formula: C12H10 N2 O8 S
  • Molecular Structure:CAS No:135459-90-4 3-Thiopheneacetic acid,5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-

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135459-90-4 3-Thiopheneacetic acid,5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-

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135459-90-4 STRONTIUM RANELATE

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References of 3-Thiopheneacetic acid,5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-
Title: Ranelic Acid
CAS Registry Number: 135459-90-4
CAS Name: 5-[Bis(carboxymethyl)amino]-2-carboxy-4-cyano-3-thiopheneacetic acid
Synonyms: 2-[N,N-di(carboxymethyl)amino]-3-cyano-4-carboxymethylthiophene-5-carboxylic acid
Molecular Formula: C12H10N2O8S
Molecular Weight: 342.28
Percent Composition: C 42.11%, H 2.94%, N 8.18%, O 37.39%, S 9.37%
Literature References: Prepn: M. Wierzbicki et al., EP 415850; eidem, US 5128367 (1991, 1992 both to Adir & Co.).
Properties: Crystals from ethyl ether, contains 4% ether.
 
Derivative Type: Strontium salt
CAS Registry Number: 135459-87-9
Synonyms: Strontium ranelate
Manufacturers' Codes: S-12911
Trademarks: Osseor (Servier); Protelos (Servier); Protos (Servier)
Molecular Formula: C12H6N2O8SSr2
Molecular Weight: 513.49
Percent Composition: C 28.07%, H 1.18%, N 5.46%, O 24.93%, S 6.24%, Sr 34.13%
Literature References: Bone metabolism modulator; inhibits bone resorption while maintaining bone formation. Effect on human chondrocytes in vitro: Y. Henrotin et al., J. Bone Miner. Res. 16, 299 (2001). Effect on bone remodeling in monkeys: J. Buehler et al., Bone 29, 176 (2001). Clinical trial in postmenopausal osteoporosis: P. J. Meunier et al., N. Engl. J. Med. 350, 459 (2004).
 
Therap-Cat: Strontium salt as antiosteoporotic.