Home > Name List By other > (5R)-5-(methoxymethyl)-3-[4-[(3R)-4,4, 4-trifluoro-3-hydroxybutoxy]phenyl]-1,3-oxazolidin-2-one

CAS No 134564-82-2 , (5R)-5-(methoxymethyl)-3-[4-[(3R)-4,4,
4-trifluoro-3-hydroxybutoxy]phenyl]-1,3-oxazolidin-2-one

  • Name: (5R)-5-(methoxymethyl)-3-[4-[(3R)-4,4,
    4-trifluoro-3-hydroxybutoxy]phenyl]-1,3-oxazolidin-2-one
  • Synonyms: befloxatone[inn];(5R)-5-(methoxymethyl)-3-[4-[(3R)-4,4,
    4-trifluoro-3-hydroxybutoxy]phenyl]-1,3-oxazolidin-2-one; Befloxatone (INN);134564-82-2;
  • CAS Registry Number:
  • Flash Point: 224.3°C
  • Boiling Point: 447.3°Cat760mmHg
  • Density: 1.326g/cm3
  • Refractive index: 1.498
  • Flash Point: 224.3°C
  • Molecular Weight: 349.30233
  • InchiKey: IALVDLPLCLFBCF-CHWSQXEVSA-N
  • InChI: InChI=1S/C15H18F3NO5/c1-22-9-12-8-19(14(21)24-12)10-2-4-11(5-3-10)23-7-
    6-13(20)15(16,17)18/h2-5,12-13,20H,6-9H2,1H3/t12-,13-/m1/s1
  • Molecular Formula: C15H18F3NO5
  • Molecular Structure:CAS No:134564-82-2 (5R)-5-(methoxymethyl)-3-[4-[(3R)-4,4,<br />4-trifluoro-3-hydroxybutoxy]phenyl]-1,3-oxazolidin-2-one

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134564-82-2 BEFLOXATONE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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134564-82-2 2-Oxazolidinone,5-(methoxymethyl)-3-[4-[(3R)-4,4,4-trifluoro-3-hydroxybutoxy]phenyl]-, (5R)-

  • China Shanghai Hao Su Chem-Tech lnc. [Manufacturers]
  • Tel: 021-6661 0036 021-5653 8833
  • Fax: (86 21) 5653 3269
  • Address: 201-204,2 BLDG,1009 North Zhong Shan Road, Shanghai Shanghai,ShanghaiChina
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134564-82-2 2-Oxazolidinone,5-(methoxymethyl)-3-[4-[(3R)-4,4,4-trifluoro-3-hydroxybutoxy]phenyl]-, (5R)-

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References of (5R)-5-(methoxymethyl)-3-[4-[(3R)-4,4,
4-trifluoro-3-hydroxybutoxy]phenyl]-1,3-oxazolidin-2-one
Title: Befloxatone
CAS Registry Number: 134564-82-2
CAS Name: (5R)-5-(Methoxymethyl)-3-[4-[(3R)-4,4,4-trifluoro-3-hydroxybutoxy]phenyl]-2-oxazolidinone
Manufacturers' Codes: MD-370503
Molecular Formula: C15H18F3NO5
Molecular Weight: 349.30
Percent Composition: C 51.58%, H 5.19%, F 16.32%, N 4.01%, O 22.90%
Literature References: Reversible monoamine oxidase type A (MAO-A) inhibitor. Prepn: F. X. Jarreau et al., EP 424244; eidem, US 5036091 (1990, 1991 both to Delalande). Pharmacology: D. Caille et al., J. Pharmacol. Exp. Ther. 277, 265 (1996). Biochemical profile: O. Curet et al., ibid. 253. Structure-activity study: J. Wouters et al., Bioorg. Med. Chem. 7, 1683 (1999). Review of clinical pharmacology: P. Rosenzweig et al., J. Affective Disord. 51, 305-312 (1998).
Properties: Crystals from ethanol + isopropyl ether, mp 101°. [a]D20 -11.5° (c = 1 in methylene chloride).
Melting point: mp 101°
Optical Rotation: [a]D20 -11.5° (c = 1 in methylene chloride)
Therap-Cat: Antidepressant.
Keywords: Monoamine Oxidase Inhibitor; Antidepressant; Phenyloxazolidinones.