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CAS No 13422-55-4 , Mecobalamin

  • Name: Mecobalamin
  • Synonyms: Methyl-5,6-dimethylbenzimidazolylcobalamin; Vitamin B12; Methyl Vitamin B12;Mecobalamin;
  • CAS Registry Number:
  • Transport: OTH
  • Safety Statements: Questionable carcinogen with experimental neoplastigenic data. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and POx.
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 236-535-3
  • Molecular Weight: 1344.38
  • InChI: InChI=1/C62H90N13O14P.CH3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3;/q;-1;+3/p-2
  • Risk Statements: 36/37/38
  • Molecular Formula: C63H91CoN13O14P
  • Molecular Structure:CAS No:13422-55-4 Mecobalamin

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13422-55-4 MECOBALAMIN

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13422-55-4 Methylcobalamine

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  • Mecobalamin 13422-55-4 Meropenem 96036-03-2 8-METHOXYPSORALEN 298-81-7 Methotrexate 1959-5-2 Mesna 19767-45-4 Methylprednisolone Aceponate 86401-95-8
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References of Mecobalamin
Title: Methylcobalamin
CAS Registry Number: 13422-55-4
CAS Name: Cobinamide Co-methyl deriv. dihydrogen phosphate (ester) inner salt 3￠-ester with 5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
Synonyms: methyl-5,6-dimethylbenzimidazolylcobalamin; mecobalamin; methyl vitamin B12; MeCbl
Trademarks: Algobaz (Labaz); Hitocobamin-M (Hishiyama); Methycobal (Eisai); Methylcobaz (Labaz)
Molecular Formula: C63H91CoN13O14P
Molecular Weight: 1344.38
Percent Composition: C 56.28%, H 6.82%, Co 4.38%, N 13.54%, O 16.66%, P 2.30%
Literature References: One of the biologically active forms of vitamin B12, q.v.; differing only by the substitution of a methyl for the cyano group. Coenzyme required in the biosynthesis of methionine. Identification as requirement for methionine biosynthesis by E. coli: R. L. Kisliuk, D. D. Woods, Biochem. J. 75, 467 (1960); J. R. Guest et al., Nature 195, 340 (1962). Prepn: O. Müller, G. Müller, Biochem. Z. 336, 299 (1962); D. Dolphin, Methods Enzymol. 18, Pt. C, 34 (1971); D. Autissier et al., Bull. Soc. Chim. Fr. 1980, part 2, 192. Interrelationship with folate metabolism: B. Shane, E. L. R. Stokstad, Annu. Rev. Nutr. 5, 115-141 (1985). Discussion of mechanism of action: W. S. Beck, Am. J. Hematol. 34, 83-89 (1990). Review: "Vitamin B12" in Vitamins, W. Friedrich, Ed. (de Gruyter, Berlin, 1988) pp 837-928.
Properties: Bright red crystals from water/acetone. uv max (pH 7): 522, 342, 266 nm (e 9357, 14416, 19897); (0.1N HCl): 462, 304, 264 nm (e 9599, 22855, 24737).
Absorption maximum: uv max (pH 7): 522, 342, 266 nm (e 9357, 14416, 19897); (0.1N HCl): 462, 304, 264 nm (e 9599, 22855, 24737)
Therap-Cat: Vitamin (hematopoietic).
Keywords: Vitamin/Vitamin Source; Vitamin B12.