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CAS No 132-92-3 , sodium

  • Name: sodium
  • Synonyms: Staficyn; Penaureus; Staphcillin;(2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,
    3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;Meticillin sodium; Synticillin; Dimocillin sodium; Celbenin; METHICILLIN SODIUM;sodium; Belfacillin;
  • CAS Registry Number:
  • Flash Point: 340.9°C
  • Boiling Point: 640°Cat760mmHg
  • Density: g/cm3
  • Safety Statements: Hazard Codes XnRisk Statements 36/37/38-42/43Safety Statements 26-36RTECS XH8950000
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 340.9°C
  • EINECS: 205-083-9
  • Molecular Weight: 402.397329
  • InchiKey: MGFZNWDWOKASQZ-UMLIZJHQSA-M
  • InChI: InChI=1S/C17H20N2O6S.Na/c1-17(2)12(16(22)23)19-14(21)11(15(19)26-17)18-
    13(20)10-8(24-3)6-5-7-9(10)25-4;/h5-7,11-12,15H,1-4H3,(H,18,20)(H,22,
    23);/q;+1/p-1/t11-,12+,15-;/m1./s1
  • Risk Statements: 36/37/38-42/43
  • Molecular Formula: C17H19N2NaO6S
  • Molecular Structure:CAS No:132-92-3 sodium

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132-92-3 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1),(2S,5R,6R)-

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132-92-3 Meticillin Sodium

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References of sodium
Title: Methicillin Sodium
CAS Registry Number: 132-92-3
CAS Name: (2S,5R,6R)-6-[(2,6-Dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monosodium salt
Synonyms: 6-(2,6-dimethoxybenzamido)penicillanic acid sodium salt; sodium 2,6-dimethoxyphenylpenicillin; 2,6-dimethoxyphenylpenicillin sodium salt; sodium 6-(2,6-dimethoxybenzamido)penicillinate; 2,6-dimethoxybenzoylpenin sodium salt; dimethoxyphenecillin sodium; sodium methicillin
Manufacturers' Codes: BRL-1241; X-1497
Trademarks: Azapen (Pfizer); Belfacillin; Celpillina; Celbenin (SKB); Cinopenil (Hoechst); Flabelline; Penistaph; Staphcillin (BMS)
Molecular Formula: C17H19N2NaO6S
Molecular Weight: 402.40
Percent Composition: C 50.74%, H 4.76%, N 6.96%, Na 5.71%, O 23.86%, S 7.97%
Literature References: Semi-synthetic antibiotic related to penicillin. Prepn starting with 6-aminopenicillanic acid: Doyle et al., J. Chem. Soc. 1962, 1457; Doyle et al., US 2951839 (1960); Glombitza, Ann. 673, 166 (1964). Physical-chemical properties: Cotta-Ramusino, Intonti, Farmaco Ed. Prat. 16, 227 (1961).
 
Derivative Type: Monohydrate
Properties: Crystals from acetone, mp 196-197° (dec). [a]D20 +230° (c = 5); +225° (c = 1). uv max: 281 nm (E1%1cm 55); min 264 nm. Solubilities (mg/ml) at 20°: water >300; ethanol 40; ether <0.03; acetone 0.35; chloroform 0.06; isooctane <0.03.
Melting point: mp 196-197° (dec)
Optical Rotation: [a]D20 +230° (c = 5); +225° (c = 1)
Absorption maximum: uv max: 281 nm (E1%1cm 55); min 264 nm
 
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antimicrobial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Penicillins.