Home > Name List By 3 > 3-hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole

CAS No 131986-45-3 , 3-hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole

  • Name: 3-hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole
  • Synonyms: Xanomeline [USAN:INN]; CHEBI:10056;LY 246708; LY-246708; LY246708;3-hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole; 131986-45-3;
  • CAS Registry Number:
  • Density: 1.101 g/cm3
  • Refractive index: 1.537
  • Molecular Weight: 281.41692
  • InchiKey: JOLJIIDDOBNFHW-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H23N3OS/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-
    12/h8H,3-7,9-11H2,1-2H3
  • Molecular Formula: C14H23N3OS
  • Molecular Structure:CAS No:131986-45-3 3-hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole

Related products

Search by region :

Select to

131986-45-3 Pyridine,3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-

  • Sweden Metina AB [Importer/Exporter]
  • Tel: +46 (0) 46 286 52 60
  • Fax: +46 (0)7 07 91 04 42
  • Address: S?lvegatan 41 Forskningsbyn IDEON 223 70 Lund Sweden IDEON,LundSweden
Contact Supplier

131986-45-3 XANOMELINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of 3-hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole
Title: Xanomeline
CAS Registry Number: 131986-45-3
CAS Name: 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine
Molecular Formula: C14H23N3OS
Molecular Weight: 281.42
Percent Composition: C 59.75%, H 8.24%, N 14.93%, O 5.69%, S 11.39%
Literature References: Selective muscarinic M1-receptor agonist. Prepn: P. Sauerberg, P. H. Olesen, EP 384288 (1990 to Ferrosan); eidem, US 5043345 (1991 to Novo Nordisk); eidem et al., J. Med. Chem. 35, 2274 (1992). Prepn of crystalline tartrate: L. M. Osborne et al., WO 9429303 (1994 to Novo Nordisk). Muscarinic receptor binding study: H. E. Shannon et al., J. Pharmacol. Exp. Ther. 269, 271 (1994). Pharmacology: F. P. Bymaster et al., ibid. 282. HPLC determn in plasma: C. L. Hamilton et al., J. Chromatogr. 613, 365 (1993).
 
Derivative Type: Oxalate
CAS Registry Number: 141064-23-5
Molecular Formula: C14H23N3OS.C2H2O4
Molecular Weight: 371.45
Percent Composition: C 51.74%, H 6.78%, N 11.31%, O 21.54%, S 8.63%
Properties: Crystals from acetone, mp 148°.
Melting point: mp 148°
 
Derivative Type: (+)-L-Hydrogen tartrate
CAS Registry Number: 152854-19-8
Synonyms: Xanomeline tartrate
Manufacturers' Codes: LY-246708; NNC-11-0232
Trademarks: Lomeron (Lilly); Memcor (Lilly)
Molecular Formula: C14H23N3OS.C4H6O6
Molecular Weight: 431.50
Percent Composition: C 50.10%, H 6.77%, N 9.74%, O 25.95%, S 7.43%
Properties: Crystals from 2-propanol, mp 95.5°.
Melting point: mp 95.5°
 
Therap-Cat: Cholinergic; nootropic.
Keywords: Cholinergic; Nootropic.