CAS No 129203-60-7 , Iberiotoxin (9CI) Search by region : China

Name: Iberiotoxin (9CI)
Synonyms: 35)-tris(disulfide);Iberiotoxin (9CI); 38: PN: WO2006116156 SEQID: 38 claimed protein;L-Glutamine, 5-oxo-L-prolyl-L-phenylalanyl-L-threonyl-L-a-aspartyl-L-valyl-L-a-aspartyl-L-cysteinyl-L-seryl-L-valyl-L-seryl-L-lysyl-L-a-glutamyl-L-cysteinyl-L-tryptophyl-L-seryl-L-valyl-L-cysteinyl-L-lysyl-L-a-aspartyl-L-leucyl-L-phenylalanylglycyl-L-valyl-L-a-aspartyl-L-arginylglycyl-L-lysyl-L-cysteinyl-L-methionylglycyl-L-lysyl-L-lysyl-L-cysteinyl-L-arginyl-L-cysteinyl-L-tyrosyl-,cyclic (7® Iberiotoxin (reduced), cyclic (7® 37: PN: WO2008088422 FIGURE: 7A claimedprotein;Charybdotoxin,4-L-aspartic acid-6-L-asparticacid-8-L-serine-9-L-valine-18-L-lysine-19-L-aspartic acid-21-L-phenylalanine-22-glycine-23-L-valine-24-L-asparticacid-30-glycine-37-L-glutamine-;28),(13®33),(17® Iberiotoxin (Buthustamulus);
CAS Registry Number:129203-60-7
Transport: UN 3462 6.1/PG 2
Flash Point: °C
Boiling Point: °Cat760mmHg
Density: g/cm³
Safety Statements: 28-36/37-45
Hazard Symbols: T+
Flash Point: °C
Molecular Weight:
InChI: InChI=1/C179H274N50O55S7/c1-87(2)65-111-155(261)208-112(66-93-33-15-13-16-34-93)146(252)195-77-133(239)225-139(88(3)4)172(278)213-117(71-136(244)245)158(264)199-100(44-31-62-190-178(186)187)144(250)193-75-131(237)198-102(40-22-27-58-181)148(254)219-124(167(273)205-109(56-64-285-12)145(251)194-76-132(238)197-101(39-21-26-57-180)147(253)200-105(43-25-30-61-184)151(257)220-123-81-286-288-83-125(221-152(258)106(203-166(123)272)45-32-63-191-179(188)189)169(275)210-113(68-95-46-48-97(234)49-47-95)156(262)206-110(177(283)284)50-53-129(185)235)82-287-291-86-128(168(274)202-104(42-24-29-60-183)150(256)212-116(70-135(242)243)159(265)207-111)224-175(281)142(91(9)10)228-164(270)121(79-231)216-157(263)115(69-96-74-192-99-38-20-19-37-98(96)99)211-170(276)126-84-289-290-85-127(171(277)217-122(80-232)165(271)227-141(90(7)8)174(280)218-120(78-230)163(269)201-103(41-23-28-59-182)149(255)204-108(154(260)222-126)52-55-134(240)241)223-160(266)118(72-137(246)247)214-173(279)140(89(5)6)226-162(268)119(73-138(248)249)215-176(282)143(92(11)233)229-161(267)114(67-94-35-17-14-18-36-94)209-153(259)107-51-54-130(236)196-107/h13-20,33-38,46-49,74,87-92,100-128,139-143,192,230-234H,21-32,39-45,50-73,75-86,180-184H2,1-12H3,(H2,185,235)(H,193,250)(H,194,251)(H,195,252)(H,196,236)(H,197,238)(H,198,237)(H,199,264)(H,200,253)(H,201,269)(H,202,274)(H,203,272)(H,204,255)(H,205,273)(H,206,262)(H,207,265)(H,208,261)(H,209,259)(H,210,275)(H,211,276)(H,212,256)(H,213,278)(H,214,279)(H,215,282)(H,216,263)(H,217,277)(H,218,280)(H,219,254)(H,220,257)(H,221,258)(H,222,260)(H,223,266)(H,224,281)(H,225,239)(H,226,268)(H,227,271)(H,228,270)(H,229,267)(H,240,241)(H,242,243)(H,244,245)(H,246,247)(H,248,249)(H,283,284)(H4,186,187,190)(H4,188,189,191)
Risk Statements: 26/27/28
Molecular Formula: C179H274 N50 O55 S7
Molecular Structure:

1/1

References of Iberiotoxin (9CI)

Title: Iberiotoxin
CAS Registry Number: 129203-60-7
Synonyms: IbTX
Literature References: Peptide inhibitor of K+ channels isolated from the venom of the scorpion, Buthus tamulus. Single polypeptide chain of 37 amino acids with 3 disulfide bridges; mol wt 4.23 kDa. Isoln, purification and characterization: A. Galvez et al., J. Biol. Chem. 265, 11083 (1990). 3D structure determn by NMR: B. A. Johnson, E. E. Sugg, Biochemistry 31, 8151 (1992). Mode of action: S. Candia et al., Biophys. J. 63, 583 (1992). Synthesis of labeled mutant: A. Koschak et al., Biochemistry 36, 1943 (1997). Use as probe: W. A. A. Kunze et al., Pflügers Arch. 428, 300 (1994); G. Fauaz et al., Vascul. Pharmacol. 40, 127 (2003); Y. Tanaka et al., Arch. Pharmacol. 367, 35 (2003).
Use: Selective probe for high-conductance calcium-activated potassium channels.

CAS No 129203-60-7 , Iberiotoxin (9CI) Search by region : China

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