Title: Quinoxyfen
CAS Registry Number: 124495-18-7
CAS Name: 5,7-Dichloro-4-(4-fluorophenoxy)quinoline
Manufacturers' Codes: DE-795
Trademarks: Fortress (Dow AgroSci.); Quintec (Dow AgroSci.)
Molecular Formula: C15H8Cl2FNO
Molecular Weight: 308.13
Percent Composition: C 58.47%, H 2.62%, Cl 23.01%, F 6.17%, N 4.55%, O 5.19%
Literature References: Quinoline fungicide for powdery mildew control in cereals, grapes and hops; inhibits formation of appressoria through which the fungus invades the plant. Prepn: W. R. Arnold
et al., EP 326330 (1989 to Eli Lilly);
eidem, US 5145843 (1992 to DowElanco). Properties and field trials: C. Longhurst
et al., Brighton Crop Prot. Conf. - Pests Dis. 1996, 27. Resistance profile: D. W. Hollomon
et al., ibid. 701. Metabolism and environmental fate: G. L. Reeves
et al., ibid. 1169. Determn and fate in grapes, raisins and wine: P. Cabras
et al., J. Agric. Food Chem. 48, 6128 (2000).
Properties: Crystals from heptane, mp 105-106°. LD50 orally in rats: >5000 mg/kg; dermally in rabbits: >2000 mg/kg; by inhalation in rats: >3.38 mg/l (Longhurst).
Melting point: mp 105-106°
Toxicity data: LD50 orally in rats: >5000 mg/kg; dermally in rabbits: >2000 mg/kg; by inhalation in rats: >3.38 mg/l (Longhurst)
Use: Agricultural fungicide.